7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine(CAS: 1269667-51-7)

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is a crystalline solid with a molecular weight of approximately 263.01 g/mol. Its solubility in water is minimal. This compound is moderately reactive and can undergo substitution reactions. It is insoluble in common organic solvents but soluble in polar aprotic solvents like dimethylformamide (DMF).

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is typically synthesized via a multistep procedure involving the reaction of 4-chloropyrrolo[2,1-f][1,2,4]triazine with bromine in the presence of a base such as sodium hydroxide. The reaction requires careful control of temperature and pH to achieve high yield and selectivity.

7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine is used in the pharmaceutical industry for the synthesis of certain drug candidates due to its structural complexity. It may also find applications in polymer chemistry for the modification of organic materials and in the development of sensors and semiconductors.

Proper handling of 7-Bromo-4-chloropyrrolo[2,1-f][1,2,4]triazine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.