Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate

Basic Information

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CAS Number

125043-04-1

Molecular Formula

C24H16F5NO4

Molecular Weight

477.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

177-181°C

Specific Rotation

+22 °(C=1, CHCl3)

SMILES

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CC(C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C24H16F5NO4/c1-11(23(31)34-22-20(28)18(26)17(25)19(27)21(22)29)30-24(32)33-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16H,10H2,1H3,(H,30,32)/t11-/m1/s1

InChIKey

CJXZXBGKOSXBFR-LLVKDONJSA-N

LogP

5.214700000000003

Topological Polar Surface Area

64.63 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

706

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AKOS015853239
AS-73993
125043-04-1
D88087
HY-W010810
DTXSID40584970
Fmoc-D-Ala-OPfp
D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,pentafluorophenyl ester(9ci)
D-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,3,4,5,6-pentafluorophenyl ester
CS-W011526
Fmoc-D-alanine pentafluorophenyl ester
(R)-perfluorophenyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)propanoate
J-005190
Fmoc-D-Ala-OPfp, >=98.0%
Pentafluorophenyl N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-alaninate
(2,3,4,5,6-pentafluorophenyl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate
2,3,4,5,6-pentafluorophenyl (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoate
MFCD00153372
Fmoc-(D)Ala-Opfp
D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, pentafluorophenyl ester (9CI)
(R)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoate
FMOC-D-ALA-OPF
REF DUPL: Fmoc-D-Ala-OPfp
(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Ala-OPfp
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-alanine pentafluorophenyl ester

MDL Number

MFCD00153372

Customs Code

29242990

FAQ

What are the physical and chemical properties of Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate (CAS: 125043-04-1)?

Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate is a crystalline compound with a molecular weight of approximately 589.7 g/mol. It has low solubility in water but is soluble in organic solvents. The compound is highly reactive due to the presence of the pentafluorophenyl group and the fluorenylmethoxy carbonyl moiety, which makes it useful in various chemical reactions.

How is Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate (CAS: 125043-04-1) typically synthesized?

Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate is typically synthesized through a multi-step process involving the coupling of a D-alanine derivative with a fluorenylmethoxycarbonyl chloride, followed by protection and deprotection steps. The synthesis often requires mild conditions and appropriate solvents to achieve high yield and selectivity.

What industries use Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate (CAS: 125043-04-1)?

Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate is used in the pharmaceutical industry for the synthesis of drug intermediates, in the polymer industry for the development of novel materials, and in the electronics industry for sensor and semiconductor applications due to its functional groups and reactivity.

What precautions should be taken when handling Pentafluorophenyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-alaninate (CAS: 125043-04-1)?

When handling this compound, it is important to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and flammable materials. Fume hood use is recommended during handling and disposal to minimize inhalation risk. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.