alpha-Iodovalerophenone

Basic Information

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CAS Number

124878-55-3

Molecular Formula

C11H13IO

Molecular Weight

288.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CCCC(C(=O)C1=CC=CC=C1)I

InChI

InChI=1S/C11H13IO/c1-2-6-10(12)11(13)9-7-4-3-5-8-9/h3-5,7-8,10H,2,6H2,1H3

InChIKey

BKVFBNAVBVPWEX-UHFFFAOYSA-N

LogP

3.4730000000000025

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

162

Synonyms & References

English

1-Pentanone, 2-iodo-1-phenyl-
alpha-Iodovalerophenone
2-iodo-1-phenyl-pentane-1-one
2-iodo-1-phenylpentan-1-one
SCHEMBL25351417
124878-55-3

FAQ

What are the physical and chemical properties of alpha-Iodovalerophenone (CAS: 124878-55-3)?

Alpha-Iodovalerophenone (CAS: 124878-55-3) is a crystalline solid with a molecular weight of approximately 265.06 g/mol. It has a characteristic odor and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive and can undergo nucleophilic substitution reactions, particularly with amines and thiols.

How is alpha-Iodovalerophenone (CAS: 124878-55-3) typically synthesized?

Alpha-Iodovalerophenone is typically synthesized by the reaction of valerophenone with iodine in the presence of a Lewis acid catalyst such as aluminum trichloride. The reaction is selective and yields high purity alpha-Iodovalerophenone with a good yield of around 70-80%.

What industries use alpha-Iodovalerophenone (CAS: 124878-55-3)?

Alpha-Iodovalerophenone (CAS: 124878-55-3) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the production of polymers and as a precursor in the development of sensors and semiconductors.

What precautions should be taken when handling alpha-Iodovalerophenone (CAS: 124878-55-3)?

When handling alpha-Iodovalerophenone (CAS: 124878-55-3), proper personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled with caution and cleaned up using appropriate solvents. Safety data sheets (SDS) should be consulted for detailed handling guidelines.