alpha-Iodovalerophenone(CAS: 124878-55-3)

Alpha-Iodovalerophenone (CAS: 124878-55-3) is a crystalline solid with a molecular weight of approximately 265.06 g/mol. It has a characteristic odor and is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive and can undergo nucleophilic substitution reactions, particularly with amines and thiols.

Alpha-Iodovalerophenone is typically synthesized by the reaction of valerophenone with iodine in the presence of a Lewis acid catalyst such as aluminum trichloride. The reaction is selective and yields high purity alpha-Iodovalerophenone with a good yield of around 70-80%.

Alpha-Iodovalerophenone (CAS: 124878-55-3) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It is also utilized in the production of polymers and as a precursor in the development of sensors and semiconductors.

When handling alpha-Iodovalerophenone (CAS: 124878-55-3), proper personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled with caution and cleaned up using appropriate solvents. Safety data sheets (SDS) should be consulted for detailed handling guidelines.