Mono-POC Isopropyl Tenofovir

Basic Information

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CAS Number

1246812-40-7

Molecular Formula

C17H28N5O7P

Molecular Weight

445.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(C)OC(=O)OCOP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC(C)C

InChI

InChI=1S/C17H28N5O7P/c1-11(2)28-17(23)25-9-27-30(24,29-12(3)4)10-26-13(5)6-22-8-21-14-15(18)19-7-20-16(14)22/h7-8,11-13H,6,9-10H2,1-5H3,(H2,18,19,20)/t13-,30?/m1/s1

InChIKey

IHJDJJPKNNEZLC-SGSXECEGSA-N

LogP

2.924900000000001

Topological Polar Surface Area

149.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 12

Complexity

597

Synonyms & References

English

Mono-POC Isopropyl Tenofovir(Mixture of Diastereomers)
Mono-POC Isopropyl T
Mono-POC Isopropyl Tenofovir
Mono-POC Isopropyl Tenofovir (Mixture of Diastereomers)
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-propan-2-yloxyphosphoryl]oxymethyl propan-2-yl carbonate
iPr-POC PMPA
Tenofovir Isopropyl Monoisoproxil
Tenofovir impurity
AMY11121
TENOFOVIR DISOPROXIL FUMARATE IMPURITY D
Mono-POC Isopropyl Tenofovir (Mixture of DiastereoMers)
[(ISOPROPOXYCARBONYL)OXY]METHYL ISOPROPYL {[(2R)-1-(6-AMINOPURIN-9-YL)PROPAN-2-YL]OXY}METHANEPHOSPHONATE
F19478
TENOFOVIR DISOPROXIL FUMARATE IMPURITY D [WHO-IP]
2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-8-methyl-5-(1-methylethoxy)-, 1-methylethyl ester, 5-oxide, (8R)-
((((((R)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate
Propan-2-yl ({[(propan-2-yl)oxy]carbonyl}oxy)methyl ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
1246812-40-7
((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate? (Tenofovir Impurity pound(c)
(1-METHYLETHYL) (5RS,8R)-9-(6-AMINO-9H-PURIN-9-YL)-8-METHYL-5-(1-METHYLETHOXY)-5-OXO-2,4,7-TRIOXA-5-.LAMBDA.5-PHOSPHANONANOATE [WHO-IP]
CS-0164363
DTXSID20858141
040YAR2IE1

MDL Number

MFCD21363855

FAQ

What is Mono-POC Isopropyl Tenofovir (CAS: 1246812-40-7)?

Mono-POC Isopropyl Tenofovir is a chemical compound with CAS number 1246812-40-7. It is a derivative of tenofovir, which is used in antiretroviral therapy. This compound is characterized by its unique structure, which includes a mono-phosphoramidate ester linkage and isopropyl substitution, making it a potential candidate for various applications in pharmaceuticals and research.

What are the main uses of Mono-POC Isopropyl Tenofovir (CAS: 1246812-40-7)?

Mono-POC Isopropyl Tenofovir is primarily used in pharmaceutical research and development, particularly in the synthesis of novel antiretroviral drugs. It can be used to evaluate the effectiveness and stability of tenofovir derivatives, and may have potential applications in the treatment of HIV/AIDS.

Is Mono-POC Isopropyl Tenofovir (CAS: 1246812-40-7) safe?

Mono-POC Isopropyl Tenofovir is generally considered safe when handled under appropriate conditions. However, it is important to follow all recommended safety precautions, including wearing appropriate personal protective equipment (PPE), such as gloves and goggles. Avoid contact with skin and eyes, and ensure proper ventilation during handling.

How should Mono-POC Isopropyl Tenofovir (CAS: 1246812-40-7) be stored?

Mono-POC Isopropyl Tenofovir should be stored in a dry, cool place away from direct sunlight and heat. It is recommended to keep it in a well-ventilated area and store it in airtight containers to prevent degradation. The storage temperature should be maintained between 15-25°C (59-77°F) to ensure optimal stability and safety.