2-Chloromethyl-4-methoxy-3-methylpyridine

Basic Information

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CAS Number

124473-12-7

Molecular Formula

C8H10ClNO

Molecular Weight

171.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CC1=C(C=CN=C1CCl)OC

InChI

InChI=1S/C8H10ClNO/c1-6-7(5-9)10-4-3-8(6)11-2/h3-4H,5H2,1-2H3

InChIKey

UIRCDHHEYPUZGA-UHFFFAOYSA-N

LogP

2.1374199999999997

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

121

Synonyms & References

English

F15214
SY257938
124473-12-7
UIRCDHHEYPUZGA-UHFFFAOYSA-N
Pyridine,2-(chloromethyl)-4-methoxy-3-methyl
2-chloromethyl-3-methyl-4--methoxypyridine
2-(chloromethyl)-4-methoxy-3-methylpyridine
EN300-224894
2-chloromethyl-3-methyl-4-methoxypyridine
AKOS006312344
Pyridine, 2-(chloromethyl)-4-methoxy-3-methyl-
SCHEMBL3393106
MFCD09859667
2-Chloromethyl-4-methoxy-3-methylpyridine
2-(CHLOROMETHYL)-4-METHOXY-3-METHYL PYRIDINE
2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride
2-(CHLOROMETHYL)-4-METHOXY-3-METHYLPYRIDINE
2-Chloromethyl-4-methoxy-3-methylpyridine hydrochloride
Ilaprazole Intermediate 1
2-Chloromethyl-4-methoxy-3-methyl-pyridine
Pyridine, 2-(chloromethyl)-4-methoxy-3-methyl
2-chloromethyl-4-methoxy-3-methylpyridine HCl
2-CHLOROMETHYL-4-METHOXY-3-METHYLPYRIDINE HYDROCHL
Pyridine, 2-(chloromethyl)-4-methoxy-3-methyl- (9CI)
2-ChloroMethyl-3-Methyl-4-Methoxypyridine Hydrochloride

MDL Number

MFCD09859667

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7)?

2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7) is a crystalline compound with a molecular weight of 244.64 g/mol. It has a melting point of 51-53°C and a boiling point of 268°C. The compound is sparingly soluble in water but has good solubility in organic solvents like ethanol and acetone. It exhibits moderate reactivity, particularly with nucleophiles and electrophiles. Chemically, it is susceptible to cleavage at the chlorine and oxygen functionalities.

How is 2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7) typically synthesized?

2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7) is typically synthesized via the reaction of 4-methoxy-3-methylpyridine with chlorine gas in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction proceeds selectively, yielding a high yield of the desired product. The process is optimized for high selectivity and yield, making it a reliable method for industrial production.

What industries use 2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7)?

2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates due to its functional groups which can be derivatized for medicinal purposes. It is also used in the polymer industry for modifying materials and in the electronic industry for sensor applications where specific chemical functionalities are required.

What precautions should be taken when handling 2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7)?

When handling 2-Chloromethyl-4-methoxy-3-methylpyridine (CAS: 124473-12-7), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. This compound should be handled in a well-ventilated area or fume hood due to its volatility. Spills should be contained and cleaned up using appropriate absorbent materials. Always consult the Material Safety Data Sheet (MSDS) for specific handling and disposal instructions to ensure safety and compliance with regulations.