![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine | CAS No. 1235318-89-4
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine
Basic Information
CAS Number
1235318-89-4
Molecular Formula
C12H12N6S
Molecular Weight
272.34 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 4-methyl-N-[5-methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-2-Pyrimidinamine
- ADX88178
- 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4- yl)thiazol-2-amine
- 2-PyriMidinaMine,4-Methyl-N-[5-Methyl-4-(1H-pyrazol-4-yl)-2-thiazolyl]-
MDL Number
MFCD21340285
FAQ
What are the physical and chemical properties of 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4)?
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is a crystalline solid with a molecular weight of approximately 332.33 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound exhibits moderate reactivity, particularly under basic conditions. Its stability is enhanced under neutral to slightly acidic conditions.
How is 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) typically synthesized?
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is synthesized using a multi-step procedure involving the condensation of 4-methylpyrimidine-2-carbaldehyde with 4-(1H-pyrazol-4-yl)thiazole-2-carbothioic acid methyl ester. The reaction proceeds with good yield and selectivity under mild conditions, utilizing a suitable catalyst and appropriate solvent.
What industries use 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4)?
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is primarily used in the pharmaceutical industry for its potential as an antitumor agent. It also has applications in the development of sensors and semiconductors due to its unique electronic properties.
What precautions should be taken when handling 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4)?
When handling 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation and skin contact. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed guidance.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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