5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine(CAS: 1235318-89-4)

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is a crystalline solid with a molecular weight of approximately 332.33 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound exhibits moderate reactivity, particularly under basic conditions. Its stability is enhanced under neutral to slightly acidic conditions.

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is synthesized using a multi-step procedure involving the condensation of 4-methylpyrimidine-2-carbaldehyde with 4-(1H-pyrazol-4-yl)thiazole-2-carbothioic acid methyl ester. The reaction proceeds with good yield and selectivity under mild conditions, utilizing a suitable catalyst and appropriate solvent.

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is primarily used in the pharmaceutical industry for its potential as an antitumor agent. It also has applications in the development of sensors and semiconductors due to its unique electronic properties.

When handling 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation and skin contact. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed guidance.