Compound Q&A

How is 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) typically synthesized?

Answer

5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine
5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine (CAS: 1235318-89-4) is synthesized using a multi-step procedure involving the condensation of 4-methylpyrimidine-2-carbaldehyde with 4-(1H-pyrazol-4-yl)thiazole-2-carbothioic acid methyl ester. The reaction proceeds with good yield and selectivity under mild conditions, utilizing a suitable catalyst and appropriate solvent.

About

English Name 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine
Molecular Formula C12H12N6S
Molecular Weight 272.34 g/mol
SMILES Cc1ccnc(n1)Nc2nc(c(s2)C)c3c[nH]nc3
InChIKey MIQNXKWDQRNHAU-UHFFFAOYSA-N
Last Updated: 2025-12-25 04:58

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