Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate | CAS No. 122188-02-7
Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate
Basic Information
CAS Number
122188-02-7
Molecular Formula
C18H23NO3
Molecular Weight
301.39 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
447.4ºC at 760 mmHg
Density
1.132 g/cm3
Flash Point
224.4ºC
Refractive Index
1.566
Synonyms & References
English
- SCHEMBL6629123
- 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano [3,4-b] indole-1-acetic acid methyl ester
- Methyl2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate
- 9ZJE4H85SV
- Methyl 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate
- FT-0655516
- Methyl1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetate
- Q-201100
- Methyl 2-[(1RS)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetate; Etodolac Imp. K (EP); Etodolac Methyl Ester; Etodolac Impurity K
- rac-Etodolac Methyl Ester
- Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, methyl ester
- UNII-9ZJE4H85SV
- Methyl ((1RS)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indol-1-yl)acetate
- 1,8-Diethyl-1,3,4,9-tetrahydropyrano-3,4-$b-indole-1-acetic acid methyl ester
- Etodolac methyl ester
- AC-4237
- 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid methyl ester
- BS-42122
- AKOS015895577
- Methyl 2-(1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indol-1-yl)acetate
- methyl 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)ethanoate
- DTXSID60881392
- ETODOLACMETHYLESTER
- methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)-indole-1-acetate
- Methyl 2-[(1RS)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl]acetate (Etodolac Methyl Ester)
- A804854
- 1,8-Diethyl-1,3,4,9-tetrahydro-pyrano[3,4-b]indole-1-acetic Acid Methyl Ester
- 122188-02-7
- MFCD02684434
- FT-0642978
- AC-7752
MDL Number
MFCD02684434
Customs Code
2942000000
FAQ
What are the physical and chemical properties of Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate (CAS: 122188-02-7)?
Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate is a crystalline compound with a molecular weight of approximately 332.42 g/mol. It has a limited water solubility and is soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, showing some susceptibility to hydrolysis and oxidation. It exhibits a characteristic UV absorbance peak at 280 nm, which can be used for analytical purposes.
How is Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate (CAS: 122188-02-7) typically synthesized?
Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate is synthesized via a multistep reaction involving the condensation of 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole with acetic anhydride. The reaction is typically carried out in the presence of a catalytic amount of a protonic acid like sulfuric acid to promote the acetylation step. The overall yield ranges from 60% to 75%, depending on the reaction conditions.
What industries use Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate (CAS: 122188-02-7)?
Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate is primarily used in the pharmaceutical industry as a precursor for the synthesis of indole derivatives with potential bioactivity. It also finds applications in the polymer and sensor industries due to its unique chemical and physical properties.
What precautions should be taken when handling Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate (CAS: 122188-02-7)?
When handling Methyl (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl)acetate, appropriate personal protective equipment (PPE) should be worn, including gloves and safety glasses. The compound should be stored in a cool, dry place away from direct sunlight. In the event of a spill, it should be handled using appropriate spill kits, and the area should be ventilated. The safety data sheet (SDS) should be consulted for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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