Gold(1+) (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate | CAS No. 12192-57-3

Gold(1+) (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate

Basic Information

CAS Number

12192-57-3

Molecular Formula

C6H11AuO5S

Molecular Weight

392.18 g/mol

AD

Basic Physical Properties

Solubility

H2O: soluble5mg/mL, clear

C(C1C(C(C(C(O1)[S-])O)O)O)O.[Au+]

InChI

InChI=1S/C6H12O5S.Au/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-10,12H,1H2;/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChIKey

XHVAWZZCDCWGBK-WYRLRVFGSA-M

LogP

-2.0187

Topological Polar Surface Area

90.15 Ų

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

160

Safety Information

View Safety Information

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

  • SPECTRUM1500132
  • NCGC00096015-01
  • KBioSS_002383
  • AUROTHIOGLUCOSE
  • CAS-12192-57-3
  • PD057378
  • Solganal
  • KBio2_007515
  • KBio2_002379
  • Pharmakon1600-01500132
  • SR-05000001568
  • KBio2_004947
  • Spectrum_001866
  • Solganol
  • Aurothioglucose hydrate
  • Aurothioglucose 80%
  • Gold thioglucose
  • SR-05000001568-1
  • CCG-213700
  • Tox21_111549
  • Gold(1+);3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate
  • NSC759601
  • SBI-0206666.P002
  • gold(1+);(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-thiolate
  • HMS2091K17
  • DTXCID3026013
  • 12192-57-3
  • DTXSID5046013
  • AB00053375_02
  • NSC-759601
  • Aurothioglucose

MDL Number

MFCD00056080

FAQ

What are the physical and chemical properties of (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3)?

The compound, (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3), is a colorless crystalline solid with a molecular weight of approximately 285.21 g/mol. It is slightly soluble in water and ethanol. Chemically, it is highly reactive, particularly with metals, and can form coordination complexes with gold ions.

How is (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3) typically synthesized?

This compound is typically synthesized through a multi-step process involving the reduction of 2,3,4,5-tetrahydroxytetrahydro-2H-pyran-6-thione with sodium borohydride, followed by the addition of gold(III) chloride to form the gold(1+) complex. The synthesis involves careful control of pH and temperature to achieve high yields and selectivity.

What industries use (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3)?

This compound finds applications in the pharmaceutical industry for its potential as a chelating agent, in the polymer industry for its ability to stabilize metal complexes, and in the semiconductor industry for its use in etching processes. It is also used in sensing applications for detecting metal ions.

What precautions should be taken when handling (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling this compound. Handling should be conducted in a fume hood to prevent inhalation. In case of a spill, use appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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