Compound Q&A

How is (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate (CAS: 12192-57-3) typically synthesized?

Answer

Gold(1+) (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate
This compound is typically synthesized through a multi-step process involving the reduction of 2,3,4,5-tetrahydroxytetrahydro-2H-pyran-6-thione with sodium borohydride, followed by the addition of gold(III) chloride to form the gold(1+) complex. The synthesis involves careful control of pH and temperature to achieve high yields and selectivity.

About

CAS No 12192-57-3
English Name Gold(1+) (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-thiolate
Molecular Formula C6H11AuO5S
Molecular Weight 392.18 g/mol
SMILES C(C1C(C(C(C(O1)[S-])O)O)O)O.[Au+]
InChIKey XHVAWZZCDCWGBK-WYRLRVFGSA-M
Last Updated: 2025-10-16 16:48

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