5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine | CAS No. 1211584-18-7

5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine

Basic Information

CAS Number

1211584-18-7

Molecular Formula

C7H7BrN4

Molecular Weight

227.07 g/mol

AD

Basic Physical Properties

CC1=NC2=NNC(=C2C=C1Br)N

InChI

InChI=1S/C7H7BrN4/c1-3-5(8)2-4-6(9)11-12-7(4)10-3/h2H,1H3,(H3,9,10,11,12)

InChIKey

FSCVFKIHSUSHBF-UHFFFAOYSA-N

LogP

1.61102

Topological Polar Surface Area

67.59 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

177

Synonyms & References

English

  • 1H-Pyrazolo[3,4-b]pyridin-3-aMine, 5-broMo-6-Methyl-
  • 5-bromo-6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine
  • L-1363 5-Bromo-6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine
  • 1H-Pyrazolo[3,4-b]pyridin-3-amine, 5-bromo-6-methyl-
  • BBL035096
  • VS-12875
  • A891874
  • AKOS023566286
  • AM86085
  • 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine
  • F18585
  • 5-Bromo-6-methyl-1,2-dihydro-3H-pyrazolo[3,4-b]pyridin-3-imine
  • CS-0321194
  • 1211584-18-7
  • DB-368575
  • STL423170

MDL Number

MFCD18254667

FAQ

What are the physical and chemical properties of 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS: 1211584-18-7)?

5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine is a crystalline solid with a molecular weight of approximately 269.04 g/mol. It is slightly soluble in water and has poor solubility in common organic solvents. This compound shows moderate reactivity with nucleophiles and can undergo substitution reactions. It is stable under normal storage conditions but should be protected from moisture and light.

How is 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS: 1211584-18-7) typically synthesized?

5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine is typically synthesized through a multi-step process involving the bromination of the corresponding methylated pyrazolo[3,4-b]pyridin-3-amine followed by reductive amination. This involves using bromine and an appropriate base, followed by a reduction step to introduce the amino functionality. The process requires careful control of reaction conditions to achieve desired selectivity and yield.

What industries use 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS: 1211584-18-7)?

5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine is used in the pharmaceutical industry for the development of new drugs. It also finds applications in the synthesis of polymers and in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS: 1211584-18-7)?

When handling 5-Bromo-6-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential reactivity. Spills should be cleaned up immediately, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

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