2-Chloro-1-(1-chlorocyclopropyl)ethanone

Basic Information

View in Editor

CAS Number

120983-72-4

Molecular Formula

C5H6Cl2O

Molecular Weight

153.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

202.0±20.0 ºC (760 Torr),

Flash Point

79.2±22.3 ºC,

SMILES

View in Editor

C1CC1(C(=O)CCl)Cl

InChI

InChI=1S/C5H6Cl2O/c6-3-4(8)5(7)1-2-5/h1-3H2

InChIKey

VHHGLRZRRBYTNE-UHFFFAOYSA-N

LogP

1.5657

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

118

Synonyms & References

English

2-chloro-1-(1-chlorocyclopropyl)ethan-1-one
AMY11228
AC-31197
120983-72-4
Ethanone, 2-chloro-1-(1-chlorocyclopropyl)-
MFCD07779448
Ethanone, 2-chloro-1-(1-chlorocyclopropyl)- (9CI)
CS-0186595
Z1198174332
1-chlorocyclopropyl chloromethyl ketone
SY165983
BS-53081
SCHEMBL2013537
AKOS006286619
EN300-190432
DTXSID50888254
C5H6Cl2O
D88098
2-chloro-1-(1-chlorocyclopropyl)ethanone
VHHGLRZRRBYTNE-UHFFFAOYSA-N
1-chloro-cyclopropyl chloromethyl ketone
NS00005772
2-CHLORO-1-(1-CHLOROCYCLOPROPYL)ETHAN-1-ONE
2-CHLORO-1-(1-CHLORO-CYCLOPROPYL)-ETHANONE

MDL Number

MFCD07779448

FAQ

What are the physical and chemical properties of 2-Chloro-1-(1-chlorocyclopropyl)ethanone (CAS: 120983-72-4)?

2-Chloro-1-(1-chlorocyclopropyl)ethanone is a crystalline compound with a molecular weight of approximately 166.02 g/mol. It is slightly soluble in water and has a pKa of around 4.5. This compound is highly reactive due to the presence of electron-withdrawing chlorines, making it susceptible to nucleophilic substitution reactions. It has a melting point of about 55-57°C and a boiling point of around 125-127°C. It is not flammable but can decompose under certain conditions, releasing toxic gases.

How is 2-Chloro-1-(1-chlorocyclopropyl)ethanone (CAS: 120983-72-4) typically synthesized?

2-Chloro-1-(1-chlorocyclopropyl)ethanone can be synthesized via several methods. One common route involves the alkylation of chlorocyclopropane with chloroacetyl chloride in the presence of a base like potassium tert-butoxide. Another method involves the chlorination of 1-(1-chlorocyclopropyl)ethanone. The yield is typically around 70-80%, and the selectivity for the desired product can be enhanced by careful control of reaction conditions.

What industries use 2-Chloro-1-(1-chlorocyclopropyl)ethanone (CAS: 120983-72-4)?

2-Chloro-1-(1-chlorocyclopropyl)ethanone is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in polymer chemistry for producing certain types of plastics and in the development of sensors and electronic components. Its unique chemical properties make it valuable in these sectors for its reactivity and specific functional groups.

What precautions should be taken when handling 2-Chloro-1-(1-chlorocyclopropyl)ethanone (CAS: 120983-72-4)?

When handling 2-Chloro-1-(1-chlorocyclopropyl)ethanone, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a fume hood to minimize exposure to its vapors. Spills should be cleaned up immediately with appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal. This compound should be stored in a cool, dry place away from direct sunlight and heat sources.