(4S)-1-Benzoyl-4-phenyl-L-proline

Basic Information

View in Editor

CAS Number

120851-71-0

Molecular Formula

C18H17NO3

Molecular Weight

295.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

View in Editor

C1C(CN(C1C(=O)O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChI=1S/C18H17NO3/c20-17(14-9-5-2-6-10-14)19-12-15(11-16(19)18(21)22)13-7-3-1-4-8-13/h1-10,15-16H,11-12H2,(H,21,22)/t15-,16+/m1/s1

InChIKey

NJMASXVCJXPDME-CVEARBPZSA-N

LogP

2.7695000000000007

Topological Polar Surface Area

57.61 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

411

Synonyms & References

English

trans-1-Benzoyl-4-phenylpyrrolidine-2-carboxylic acid
AM20020294
A804604
(2S,4S)-1-benzoyl-4-phenylpyrrolidine-2-carboxylic acid
NJMASXVCJXPDME-CVEARBPZSA-N
AKOS015889663
94005-34-2
trans-1-benzoyl-4-phenyl-l-proline
Proline,1-benzoyl-4-phenyl-
1-Benzoyl-4-phenylproline
120851-71-0
SCHEMBL10469216
L-Proline, 1-benzoyl-4-phenyl-, trans- (9CI)
DTXSID80923581
(Trans)-1-benzoyl-4-phenyl-L-proline
Q-100101
TRANS-1-BENZOYL-4-PHENYL-L-PROLINE (INTERMEDIATE OF FOSINOPRIL )
trans-1-benzoyl-4-phenyl-L-proline
trans-1-Benzoyl-4-ph

MDL Number

MFCD08063936

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (4S)-1-Benzoyl-4-phenyl-L-proline (CAS: 120851-71-0)?

(4S)-1-Benzoyl-4-phenyl-L-proline is a white crystalline compound with a molecular weight of approximately 325.32 g/mol. It has a melting point of 215-217 °C and is slightly soluble in water. This compound is known for its stability and reactivity under certain conditions, making it suitable for various chemical applications.

How is (4S)-1-Benzoyl-4-phenyl-L-proline (CAS: 120851-71-0) typically synthesized?

(4S)-1-Benzoyl-4-phenyl-L-proline can be synthesized through a Friedel-Crafts acylation reaction of 4-phenyl-L-proline with benzoyl chloride in the presence of aluminum chloride as a catalyst. This method provides good yield and selectivity, and the reaction is generally performed under mild conditions.

What industries use (4S)-1-Benzoyl-4-phenyl-L-proline (CAS: 120851-71-0)?

(4S)-1-Benzoyl-4-phenyl-L-proline is used in the pharmaceutical industry for the synthesis of certain drugs and as a chiral auxilary. It also finds applications in the polymer industry for the modification of polymer properties and in the semiconductor industry as a dopant.

What precautions should be taken when handling (4S)-1-Benzoyl-4-phenyl-L-proline (CAS: 120851-71-0)?

When handling (4S)-1-Benzoyl-4-phenyl-L-proline, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure that the substance is handled in a well-ventilated area or a fume hood to minimize exposure. In the event of a spill, use appropriate absorbent materials and follow the material safety data sheet (MSDS) for disposal and cleanup instructions.