Compound Q&A

How is (4S)-1-Benzoyl-4-phenyl-L-proline (CAS: 120851-71-0) typically synthesized?

Answer

(4S)-1-Benzoyl-4-phenyl-L-proline
(4S)-1-Benzoyl-4-phenyl-L-proline can be synthesized through a Friedel-Crafts acylation reaction of 4-phenyl-L-proline with benzoyl chloride in the presence of aluminum chloride as a catalyst. This method provides good yield and selectivity, and the reaction is generally performed under mild conditions.

About

English Name (4S)-1-Benzoyl-4-phenyl-L-proline
Molecular Formula C18H17NO3
Molecular Weight 295.34 g/mol
SMILES C1C(CN(C1C(=O)O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
InChIKey NJMASXVCJXPDME-CVEARBPZSA-N
Last Updated: 2025-10-29 13:16

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