2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole | CAS No. 1193272-59-1
2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole
Basic Information
CAS Number
1193272-59-1
Molecular Formula
C17H17ClN2OS
Molecular Weight
332.86 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 2-(4-chloro-7-methoxy-8-methyl-2-quinolyl)-4-isopropyl-thiazole
- 2-(4-isopropyl-thiazol-2-yl)-4-chloro-7-methoxy-8-methyl-quinoline
- 2-(4-chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole
- PNVZYJFBBFNRPK-UHFFFAOYSA-N
- 4-chloro-2-(4-isopropyl-thiazol-2-yl)-7-methoxy-8-methyl-quinoline
- 2-(4-isopropylthiazol-2-yl)-4-chloro-7-methoxy-8-methyl-quinoline
- 2-(4-isopropylthiazol-2-yl)-4-cloro-7-methoxy-8-methyl-quinoline
- 1193272-59-1
- SCHEMBL874861
- Quinoline, 4-chloro-7-methoxy-8-methyl-2-[4-(1-methylethyl)-2-thiazolyl]-
- CS-M0644
- DB-312663
- 2-(4-chloro-7-methoxy-8-methylquinolin-2-yl)-4-propan-2-yl-1,3-thiazole
- 4-CHLORO-2-(4-ISOPROPYL-1,3-THIAZOL-2-YL)-7-METHOXY-8-METHYLQUINOLINE
- CS-13683
- AKOS037649804
MDL Number
MFCD18642759
FAQ
What are the physical and chemical properties of 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole (CAS: 1193272-59-1)?
2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole is a crystalline solid with a molecular weight of approximately 419.84 g/mol. It is slightly soluble in water and has a low solubility in common organic solvents. This compound is relatively stable under normal conditions but may react with strong oxidizing agents. It shows favorable reactivity towards nucleophilic substitution reactions.
How is 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole (CAS: 1193272-59-1) typically synthesized?
2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole can be synthesized via a multi-step process involving the coupling of 4-chloro-7-methoxy-8-methylquinoline with 4-isopropylthiophenol. This synthesis typically uses a palladium catalyst under microwave-assisted conditions, providing high yield and selectivity. The reaction is performed under inert atmosphere to prevent oxidation.
What industries use 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole (CAS: 1193272-59-1)?
2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole is used in the pharmaceutical industry for its potential biological activities. It may also find applications in the polymer industry as a functional monomer, in the sensor industry for detecting specific chemical species, and in the semiconductor industry as a precursor in organic semiconductor materials.
What precautions should be taken when handling 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole (CAS: 1193272-59-1)?
Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole. The compound should be handled in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be immediately contained and cleaned up using appropriate absorbents. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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