2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole(CAS: 1193272-59-1)

2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole is a crystalline solid with a molecular weight of approximately 419.84 g/mol. It is slightly soluble in water and has a low solubility in common organic solvents. This compound is relatively stable under normal conditions but may react with strong oxidizing agents. It shows favorable reactivity towards nucleophilic substitution reactions.

2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole can be synthesized via a multi-step process involving the coupling of 4-chloro-7-methoxy-8-methylquinoline with 4-isopropylthiophenol. This synthesis typically uses a palladium catalyst under microwave-assisted conditions, providing high yield and selectivity. The reaction is performed under inert atmosphere to prevent oxidation.

2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole is used in the pharmaceutical industry for its potential biological activities. It may also find applications in the polymer industry as a functional monomer, in the sensor industry for detecting specific chemical species, and in the semiconductor industry as a precursor in organic semiconductor materials.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 2-(4-Chloro-7-methoxy-8-methylquinolin-2-yl)-4-isopropylthiazole. The compound should be handled in a well-ventilated area or fume hood to minimize inhalation risk. Spills should be immediately contained and cleaned up using appropriate absorbents. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).