5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole | CAS No. 119141-89-8
5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole
Basic Information
CAS Number
119141-89-8
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
600°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- (R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
- (R)-Omeprazole
- Esomeprazole Impurity F
- OMEPRAZOLE
- R-(+)-OMEPRAZOLE
- ANTRA
- GASTROGARD
- GASTROLOC
- H 168
- LOSEC
- MEPRAL
- MOPRAL
- OMEPRAL
- PRILOSEC
- ZOLTUM
- Esomeprazole
- AK101106
- Nexiam
- (+)-omeprazole
- Esomeprazole [INN:BAN]
- S51HU491WJ
- (R)-(+)-omeprazole
- 5-Methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
- 1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-
- SB17370
- (R)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
MDL Number
MFCD00083192
Customs Code
2941500000
FAQ
What are the physical and chemical properties of 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole (CAS: 119141-89-8)?
5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is a crystalline solid with a molecular weight of approximately 374.41 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound is chemically stable but reacts with strong oxidizing agents. It has good thermal stability up to about 250°C.
How is 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole (CAS: 119141-89-8) typically synthesized?
5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is synthesized through a multi-step process involving the reaction of 4-methoxy-3,5-dimethyl-2-pyridinylmethylthio compound with benzimidazole. The method involves the use of a palladium catalyst under basic conditions. The overall yield is around 70-80%, with high selectivity to the desired product.
What industries use 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole (CAS: 119141-89-8)?
5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for enhancing the properties of certain polymers and in the semiconductor industry for use in sensor technologies.
What precautions should be taken when handling 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole (CAS: 119141-89-8)?
When handling 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the use of a fume hood during handling to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, follow the safety data sheet (SDS) guidelines for disposal and clean up.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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