5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole(CAS: 119141-89-8)

5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is a crystalline solid with a molecular weight of approximately 374.41 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound is chemically stable but reacts with strong oxidizing agents. It has good thermal stability up to about 250°C.

5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is synthesized through a multi-step process involving the reaction of 4-methoxy-3,5-dimethyl-2-pyridinylmethylthio compound with benzimidazole. The method involves the use of a palladium catalyst under basic conditions. The overall yield is around 70-80%, with high selectivity to the desired product.

5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for enhancing the properties of certain polymers and in the semiconductor industry for use in sensor technologies.

When handling 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Ensure the use of a fume hood during handling to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, follow the safety data sheet (SDS) guidelines for disposal and clean up.