a-Bromo-N-Boc-Gly-OtBu

Basic Information

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CAS Number

117833-60-0

Molecular Formula

C11H20BrNO4

Molecular Weight

310.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

55 ºC

SMILES

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CC(C)(C)OC(=O)C(NC(=O)OC(C)(C)C)Br

InChI

InChI=1S/C11H20BrNO4/c1-10(2,3)16-8(14)7(12)13-9(15)17-11(4,5)6/h7H,1-6H3,(H,13,15)

InChIKey

RBGAAZPKHKBDGM-UHFFFAOYSA-N

LogP

2.5738000000000003

Topological Polar Surface Area

64.63 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

291

Synonyms & References

English

MFCD16038246
AKOS015908727
tert-Butyl 2-(Boc-amino)-2-bromoacetate
DTXSID80454441
Bromo-tert-butoxycarbonylamino-acetic acid tert-butyl ester
FT-0603915
A-BROMO-N-BOC-GLY-OTBU
tert-Butyl2-bromo-2-((tert-butoxycarbonyl)amino)acetate
t-Butyl 2-bromo-2-((tert-butoxycarbonyl)amino)acetate
SCHEMBL1352479
SY286542
RBGAAZPKHKBDGM-UHFFFAOYSA-N
C93227
117833-60-0
Alfa-Bromo-N-Boc-Gly-OtBu
tert-Butyl 2-bromo-2-((tert-butoxycarbonyl)amino)acetate
Tert-butyl 2-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate
AMY25354
tert-butyl 2-bromo-2-(tert-butoxycarbonyl)acetate
Acetic acid,2-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester
a-Bromo-N-Boc-Gly-OtBu
tert-butyl 2-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate
Α-BROMO-N-BOC-GLY-OTBU
tert-butyl N-Boc-bromoglycinate
Aceticacid, bromo[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester(9CI)

MDL Number

MFCD16038246

Customs Code

2924199090

FAQ

What are the physical and chemical properties of a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0)?

a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0) is a crystalline compound with a molecular weight of approximately 357.02 g/mol. It has a low solubility in water but is moderately soluble in common organic solvents such as methanol and dichloromethane. The compound is moderately reactive, particularly towards nucleophiles due to its bromine substituent. It is used in various organic synthesis reactions, particularly in protecting group chemistry.

How is a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0) typically synthesized?

a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0) is typically synthesized through a multistep process involving the introduction of a tert-butyl group followed by the attachment of a bromine atom to the amino group of N-Boc-Glycine. This synthesis often uses bromine in the presence of a suitable base, such as sodium hydride, and is optimized for high yield and selectivity.

What industries use a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0)?

a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0) is primarily used in the pharmaceutical and biotechnology industries for the synthesis of complex molecules and drug candidates. It is also utilized in polymer chemistry for the development of novel materials and in analytical chemistry for the enhancement of sensor technologies.

What precautions should be taken when handling a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0)?

When handling a-Bromo-N-Boc-Gly-OtBu (CAS: 117833-60-0), ensure the use of appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure to bromine vapor. Store the compound in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, follow standard laboratory safety protocols and consult the safety data sheet (SDS) for specific instructions.