1-(4-Fluorophenyl)-4-piperidinone | CAS No. 116247-98-4
1-(4-Fluorophenyl)-4-piperidinone
Basic Information
CAS Number
116247-98-4
Molecular Formula
C11H12FNO
Molecular Weight
193.22 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 4-Piperidinone, 1-(4-fluorophenyl)-
- BB 0252256
- AKOS000176992
- AB22775
- Z295882106
- N-(4-fluorophenyl)-4-oxo-piperidine
- 1-(4-fluorophenyl)piperidin-4-one
- CS-0441374
- 1-(P-FLUOROPHENYL)-4-PIPERIDONE
- AM802997
- 1-(4-fluorophenyl)-4-piperidinone
- 1-(4-fluorophenyl)-4-piperidone
- N-(4-fluorophenyl)-piperidin-4-one
- EN300-52086
- SCHEMBL61987
- 116247-98-4
- MFCD05864502
- AS-39494
- DTXSID70345672
- 1-(4-fluoro-phenyl)piperidin-4-one
- A803579
- 1-(4-FLUORO-PHENYL)-PIPERIDIN-4-ONE
- 1-(4-Fluorophenyl)piperidin-4-one
- 4-Piperidinone,1-(4-fluorophenyl)-
- N-(4-Fluorophenyl)-4-oxo-piperidine
- 1-(p-fluorophenyl)-4-piperidone
- 4-Piperidinone,1-(4-fluorophenyl)
- CHEMBRDG-BB 4000326
- 1-(4-Fluorophenyl)piperidine-4-one
- 1-N-(4'-FLUOROPHENYL)-PIPERIDIN-4-ONE
- 1-(4-fluorophenyl)piperidin-4-one(SALTDATA: FREE)
MDL Number
MFCD05864502
FAQ
What are the physical and chemical properties of 1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4)?
1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4) is a white to off-white crystalline solid with a molecular weight of approximately 223.22 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and DMSO. Chemically, it is relatively stable but can undergo hydrolysis under basic conditions. It is a useful intermediate in pharmaceutical and chemical synthesis.
How is 1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4) typically synthesized?
1-(4-Fluorophenyl)-4-piperidinone can be synthesized via a direct fluorination of 1-(4-hydroxyphenyl)-4-piperidinone or through amination of 4-fluorophenol followed by oxidation. Commonly, this involves the use of trifluoroacetic anhydride or other fluorinating agents. The reaction typically provides good yield with high selectivity.
What industries use 1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4)?
1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various pharmaceutical compounds. It is also explored in polymer chemistry for its potential in the development of advanced materials and in sensor technology for its chemical reactivity.
What precautions should be taken when handling 1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4)?
When handling 1-(4-Fluorophenyl)-4-piperidinone (CAS: 116247-98-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled in a fume hood, and proper waste disposal procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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