3-Iodopyridine

Basic Information

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CAS Number

1120-90-7

Molecular Formula

C5H4IN

Molecular Weight

205 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

53.0 to 56.0 deg-C

Boiling Point

92°C/14mmHg

Refractive Index

1.629

SMILES

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C1=CC(=CN=C1)I

InChI

InChI=1S/C5H4IN/c6-5-2-1-3-7-4-5/h1-4H

InChIKey

XDELKSRGBLWMBA-UHFFFAOYSA-N

LogP

1.6861999999999997

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class LIGHT SENSITIVE Class LIGHT SENSITIVE

Sensitiveness

Light Sensitive

Synonyms & References

English

BP-21358
AB01382
SCHEMBL10515
FT-0615915
BB 0267981
3-Pyridyl iodide; NSC 5076
CS-D1693
XDELKSRGBLWMBA-UHFFFAOYSA-N
Pyridine, 3-iodo-
W-109016
LWL4FC4MZM
I0568
EN300-71344
AC-7558
EINECS 214-322-6
AC-907/30003005
A1388
AS-14543
NS00023601
UNII-LWL4FC4MZM
CL0133
AKOS005207203
3-Iodo-pyridine
SY007548
3-Iodo pyridine
NSC5076
1120-90-7
3-Iodopyridine
BCP21598
InChI=1/C5H4IN/c6-5-2-1-3-7-4-5/h1-4
DTXSID10149813

MDL Number

MFCD00023553

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Iodopyridine (CAS: 1120-90-7)?

3-Iodopyridine (CAS: 1120-90-7) is a yellowish solid with a crystalline form. It has a molecular weight of approximately 213.02 g/mol. The compound is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it exhibits basic properties due to the presence of the pyridine ring and can undergo nucleophilic substitution reactions at the iodine position.

How is 3-Iodopyridine (CAS: 1120-90-7) typically synthesized?

3-Iodopyridine can be synthesized via the reaction of 2-chloropyridine with iodine in the presence of a base such as potassium carbonate. The reaction is conducted in an aprotic solvent like acetonitrile. This method provides good selectivity and yield, making it a common route for industrial synthesis.

What industries use 3-Iodopyridine (CAS: 1120-90-7)?

3-Iodopyridine (CAS: 1120-90-7) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the chemical industry for the production of dyes and pigments. Additionally, it is used in the development of sensors and electronic materials.

What precautions should be taken when handling 3-Iodopyridine (CAS: 1120-90-7)?

When handling 3-Iodopyridine (CAS: 1120-90-7), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. The compound should be stored in a well-ventilated area and used in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed safety information.