3-Iodopyridine(CAS: 1120-90-7)

3-Iodopyridine (CAS: 1120-90-7) is a yellowish solid with a crystalline form. It has a molecular weight of approximately 213.02 g/mol. The compound is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it exhibits basic properties due to the presence of the pyridine ring and can undergo nucleophilic substitution reactions at the iodine position.

3-Iodopyridine can be synthesized via the reaction of 2-chloropyridine with iodine in the presence of a base such as potassium carbonate. The reaction is conducted in an aprotic solvent like acetonitrile. This method provides good selectivity and yield, making it a common route for industrial synthesis.

3-Iodopyridine (CAS: 1120-90-7) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the chemical industry for the production of dyes and pigments. Additionally, it is used in the development of sensors and electronic materials.

When handling 3-Iodopyridine (CAS: 1120-90-7), it is important to wear appropriate personal protective equipment (PPE), including gloves and goggles. The compound should be stored in a well-ventilated area and used in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed safety information.