(S)-Alpha,Alpha-Diphenylmethylprolinol

Basic Information

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CAS Number

110529-22-1

Molecular Formula

C18H21NO

Molecular Weight

267.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

68.0 to 72.0 deg-C

Boiling Point

406.8±25.0 °C at 760 mmHg

Density

1.1±0.1 g/cm3

Flash Point

196.8±21.8 °C

Refractive Index

55 ° (C=1, CHCl3)

Specific Rotation

+52° (c=1, CHCl3)

SMILES

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O[C@@H](C(C1=CC=CC=C1)C2=CC=CC=C2)C3NCCC3

InChI

1S/C18H21NO/c20-14-17-12-7-13-19(17)18(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,17-18,20H,7,12-14H2/t17-/m0/s1

InChIKey

XIJAGFLYYNXCAB-KRWDZBQOSA-N

LogP

2.931400000000001

Topological Polar Surface Area

32.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

287

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-Alpha,Alpha-Diphenylmethylprolinol
alpha,alpha-Diphenyl-N-methyl-L-prolinol
(S)-alpha,alpha-Diphenyl-N-methyl-2-pyrrolidinemethanol
Hydroxydiphenylmethylmethylpyrrolidine
(S)-N-Methyl-alpha,alpha-diphenylpyrrolidinemethanol
(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine
(S)-a,a-Diphenylmethylprolinol
(1-methylpyrrolidin-2-yl)(diphenyl)methanol
(2S)-2-[hydroxy(diphenyl)methyl]-1-methylpyrrolidinium
(S)-N-Methyl-alpha,alpha-diphenyl2-pyrrolidine methanol
[(2S)-1-methylpyrrolidin-2-yl](diphenyl)methanol
α,α-Diphenyl-N-methyl-L-prolinol
(S)-(+)-Diphenyl(1-methylpyrrolidin-2-yl)methanol
(2S)-(+)-N-Methyl-α
1,1-Diphenyl-N-methyl-L-prolinol
à,à-diphenyl-n-methyl-l-prolinol
a,a-Diphenyl-N-methyl-L-prolinol
(S)-N-Methyl-alpha,alpha-diphenyl
(S)-A,A-DIPHENYLMETHYLPROLINOL
α,α-diphenyl-n-methyl-l-prolinol
(S)-ALPHA,ALPHA-DIPHENYLMETHYLPROLINOL
ALPHA,ALPHA-DIPHENYL-N-METHYL-L-PROLINOL

MDL Number

MFCD00145245

FAQ

What is (S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1)?

(S)-Alpha,Alpha-Diphenylmethylprolinol, also known as (S)-2-(diphenylmethyl)-2-phenylpropan-1-ol, is a chiral organic compound with the CAS number 110529-22-1. It is a white or off-white solid with a characteristic odor and a molecular formula of C21H24O. This compound is often used in pharmaceuticals, as a chiral auxiliary, and in organic synthesis due to its structural features.

What are the main uses of (S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1)?

(S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1) is primarily used as a chiral auxiliary in pharmaceutical and organic synthesis applications. It is also utilized in the preparation of chiral compounds and in the development of enantioselective reactions. Additionally, it has some potential applications in the food industry for flavor and aroma compounds.

Is (S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1) safe?

(S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1) is generally safe when handled with proper precautions. It is important to avoid skin contact and inhalation of dust. Protective gloves and eye protection should be worn during handling. It is also advisable to work in a well-ventilated area and store in a cool, dry place away from direct sunlight and sources of ignition.

How should (S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1) be stored?

(S)-Alpha,Alpha-Diphenylmethylprolinol (CAS: 110529-22-1) should be stored in a tightly sealed container in a cool, dry place, protected from moisture and light. It should be kept at a temperature below 25°C and away from heat sources and direct sunlight. Storage in a desiccator may be necessary to maintain its quality and stability.