Concanavalin A

Basic Information

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CAS Number

11028-71-0

Molecular Formula

C23H32N6O8S

Molecular Weight

552.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Water Solubility

Slightly soluble in water and phosfate buffered saline.

Flash Point

39 °C

Solubility

PBS: 5 mg/mL, slightly hazy

SMILES

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CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(=O)O.CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]

InChI

1S/C13H19NO4S.C10H13N5O4/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16;1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h5-8H,3-4,9-10H2,1-2H3,(H,15,16);3,6-8,16H,2,4H2,1H3,(H,12,17,18)

InChIKey

RVSZVJZFCQZYHQ-UHFFFAOYSA-N

Complexity

858

Safety Information

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GHS Hazard Pictograms

H317

H334

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Synonyms & References

English

Concanavalin A
ConA Type A IV
CONCANAVALIN A BR
Concanavalin A lectin (Con A)
CONCANAVALIN A TYPE III
Concanavalin A from Canavalia ensiformis (jack bean)
Ricin-toxin con A
CON A
nsc143504
CONCANAVALIN
CON A TYPE IV
concanavalinea
A,concanavalin
CONCANAVALIN A TYPE
Concanavalin A III
Concanalin A (Con A)
Concanavaline A
1-[4-Azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione;4-(dipropylsulfamoyl)benzoic a

MDL Number

MFCD00071069

Customs Code

35040090

FAQ

What are the physical and chemical properties of Concanavalin A (CAS: 11028-71-0)?

Concanavalin A (ConA, CAS: 11028-71-0) is a glycoprotein with a molecular weight of approximately 40 kDa. It is a white to pale yellow crystalline powder with good solubility in water and methanol. ConA is known for its high reactivity towards glycoproteins, showing strong affinity for sugars, particularly N-acetylglucosamine. It is a protein with pH-dependent conformational changes and can form stable complexes with glycoproteins under specific conditions.

How is Concanavalin A (CAS: 11028-71-0) typically synthesized?

Concanavalin A (ConA, CAS: 11028-71-0) is typically synthesized through a combination of fermentation and chemical modification. It is initially produced by the fungus Canavalia ensiformis (jack bean) through fermentation processes. Subsequent chemical modifications can alter its properties, such as conjugation with other molecules to enhance its functionality in various applications. The synthesis involves controlled conditions and the use of appropriate catalysts to achieve high yield and selectivity.

What industries use Concanavalin A (CAS: 11028-71-0)?

Concanavalin A (ConA, CAS: 11028-71-0) is widely used in various industries. In pharmaceuticals, it is utilized for drug discovery and as a research tool. In biotechnology, ConA serves as a specific binding reagent for glycoproteins. It is also employed in the food industry as a quality control tool for detecting glycoproteins. Additionally, ConA finds applications in the development of biosensors and semiconductors due to its unique binding properties.

What precautions should be taken when handling Concanavalin A (CAS: 11028-71-0)?

When handling Concanavalin A (ConA, CAS: 11028-71-0), it is essential to follow proper laboratory safety protocols. Wear appropriate personal protective equipment (PPE), such as gloves and goggles, and work in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate chemicals or methods, and all waste should be disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.