Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate

Basic Information

View in Editor

CAS Number

1099-87-2

Molecular Formula

C19H27NaO5S

Molecular Weight

390.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

148-149 °C (dec.)

Boiling Point

°Cat760mmHg

Flash Point

9℃

Solubility

methanol: clear to hazy

Refractive Index

10 ° (C=4, MeOH)

SMILES

View in Editor

CC12CCC3C(C1CCC2=O)CC=C4C3(CCC(C4)OS(=O)(=O)[O-])C.[Na+]

InChI

InChI=1S/C19H28O5S.Na/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18;/h3,13-16H,4-11H2,1-2H3,(H,21,22,23);/q;+1/p-1/t13-,14-,15-,16-,18-,19-;/m0./s1

InChIKey

GFJWACFSUSFUOG-ZJTJBYBXSA-M

LogP

4.44450

Complexity

727

Synonyms & References

English

sodium prasterone sulfate
NSC 72822
H11595
Teloin
Dehydroisoandrosterone sulfate sodium salt
Sodium (3beta)-androst-5-en-17-one 3-sulphate
B9840IHU4T
Androst-5-en-17-one, 3.beta.-hydroxy-, hydrogen sulfate, sodium salt
3beta-Hydroxy-5-androsten-17-one sodium sulfate dihydrate
dehydroepiandrosterone sodium sulfate
SCHEMBL606953
Dehydroisoandrosterone sulfate sodium sal
Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate
Dehydroisoandrosterone 3-sulfate sodium
Prasterone sodium sulfate
Sodium prasterone sulfate [JAN]
Q27163028
Androst-5-en-17-one, 3-(sulfooxy)-, sodium salt, (3-beta)-
sodium (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-oxo-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl sulfate
DEHYDROEPIANDROSTERONE-3-SULFATE SODIUM
CS-0009649
Dehydroepiandrosterone sulfate (sodium salt)
Dehydroepiandrosterone sulfate sodium salt
CHEBI:91028
DTXSID00273954
PRASTERONE SODIUM SULFATE ANHYDROUS
Dehydroepiandrosterone 3-sulfate sodium
Sodium Dehydroisoandrosterone-3-sulfate
CHEMBL1573900
Dehydroepiandrosterone sulfate sodium
HY-B0765

MDL Number

MFCD00010470

FAQ

What are the physical and chemical properties of Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2)?

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2) is a white to off-white crystalline solid with a molecular weight of approximately 588.66 g/mol. It is poorly soluble in water but has good solubility in organic solvents. The compound is moderately reactive, particularly in acidic environments, where it can undergo hydrolysis. It is stable under normal laboratory conditions but should be stored in airtight containers to prevent moisture absorption.

How is Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2) typically synthesized?

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate is synthesized via a multi-step process involving the conversion of androst-5-en-3-one to (3beta)-17-oxoandrost-5-en-3-one, followed by its esterification with sulfuric acid to form the sulfate ester. This process typically requires careful control of reaction conditions, including temperature and pH, to achieve high yield and selectivity. Common catalysts include sulfuric acid and other strong acids.

What industries use Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2)?

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2) is primarily used in the pharmaceutical industry for the synthesis of progestins and other steroid hormones. It is also explored in research for its potential applications in polymers and materials science, particularly in the development of novel drug delivery systems and sensor technologies.

What precautions should be taken when handling Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2)?

When handling Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.