Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate(CAS: 1099-87-2)

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2) is a white to off-white crystalline solid with a molecular weight of approximately 588.66 g/mol. It is poorly soluble in water but has good solubility in organic solvents. The compound is moderately reactive, particularly in acidic environments, where it can undergo hydrolysis. It is stable under normal laboratory conditions but should be stored in airtight containers to prevent moisture absorption.

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate is synthesized via a multi-step process involving the conversion of androst-5-en-3-one to (3beta)-17-oxoandrost-5-en-3-one, followed by its esterification with sulfuric acid to form the sulfate ester. This process typically requires careful control of reaction conditions, including temperature and pH, to achieve high yield and selectivity. Common catalysts include sulfuric acid and other strong acids.

Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2) is primarily used in the pharmaceutical industry for the synthesis of progestins and other steroid hormones. It is also explored in research for its potential applications in polymers and materials science, particularly in the development of novel drug delivery systems and sensor technologies.

When handling Sodium (3beta)-17-oxoandrost-5-en-3-yl sulfate (CAS: 1099-87-2), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.