(1-Methyl-1H-indazol-6-YL)methanol

Basic Information

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CAS Number

1092961-10-8

Molecular Formula

C9H10N2O

Molecular Weight

162.19 g/mol

Basic Physical Properties

SMILES

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CN1C2=C(C=CC(=C2)CO)C=N1

InChI

InChI=1S/C9H10N2O/c1-11-9-4-7(6-12)2-3-8(9)5-10-11/h2-5,12H,6H2,1H3

InChIKey

BVPUKTSBKDFGBN-UHFFFAOYSA-N

LogP

1.0655999999999999

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

163

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1-Methyl-1H-indazol-6-yl)methanol
6-(Hydroxymethyl)-1-methyl-1H-indazole
(1-methylindazol-6-yl)methanol
BVPUKTSBKDFGBN-UHFFFAOYSA-N
1-Methyl-1H-indazole-6-methanol
FCH887840
RP02242
PB23861
(1-Methyl-1H-indazol-6-yl);methanol
WT82580
OR30863
6-HYDROXYMETHYL-1-METHYLINDAZOLE
SY101715
AB0037861
ST1100661
AX8167784
TC
Y5193
(1-methyl-1H-indazol-6-yl)methanol
DTXSID30657127
1092961-10-8
J-500218
DB-059873
CS-0043867
MFCD11052638
AKOS006308392
DS-17638
AMY33946
W-204711
(1-METHYL-1H-INDAZOL-6-YL)METHANOL
SCHEMBL14800197

MDL Number

MFCD06800918

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (1-Methyl-1H-indazol-6-YL)methanol (CAS: 1092961-10-8)?

(1-Methyl-1H-indazol-6-YL)methanol is a crystalline solid with a molecular weight of approximately 194.24 g/mol. It has a high solubility in polar solvents like ethanol and methanol but is only slightly soluble in water. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but can degrade upon prolonged exposure to light and moisture.

How is (1-Methyl-1H-indazol-6-YL)methanol (CAS: 1092961-10-8) typically synthesized?

(1-Methyl-1H-indazol-6-YL)methanol is typically synthesized via the reaction of 1-methylindazole with methanol in the presence of a catalyst like a strong acid such as sulfuric acid. The process yields a high purity product with good selectivity and a yield of around 85-90%. The reaction is conducted under mild conditions to ensure the desired product is formed.

What industries use (1-Methyl-1H-indazol-6-YL)methanol (CAS: 1092961-10-8)?

(1-Methyl-1H-indazol-6-YL)methanol finds application in the pharmaceutical industry, particularly in the synthesis of bioactive compounds and drug intermediates. It is also utilized in the polymer industry for the development of advanced materials, and in sensor technology for its potential as a sensing element. Its use in semiconductors is less common but explores its electronic properties.

What precautions should be taken when handling (1-Methyl-1H-indazol-6-YL)methanol (CAS: 1092961-10-8)?

When handling (1-Methyl-1H-indazol-6-YL)methanol, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up carefully using absorbent materials, and the area should be thoroughly rinsed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.