(1-Methyl-1H-indazol-6-YL)methanol(CAS: 1092961-10-8)

(1-Methyl-1H-indazol-6-YL)methanol is a crystalline solid with a molecular weight of approximately 194.24 g/mol. It has a high solubility in polar solvents like ethanol and methanol but is only slightly soluble in water. This compound exhibits moderate reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but can degrade upon prolonged exposure to light and moisture.

(1-Methyl-1H-indazol-6-YL)methanol is typically synthesized via the reaction of 1-methylindazole with methanol in the presence of a catalyst like a strong acid such as sulfuric acid. The process yields a high purity product with good selectivity and a yield of around 85-90%. The reaction is conducted under mild conditions to ensure the desired product is formed.

(1-Methyl-1H-indazol-6-YL)methanol finds application in the pharmaceutical industry, particularly in the synthesis of bioactive compounds and drug intermediates. It is also utilized in the polymer industry for the development of advanced materials, and in sensor technology for its potential as a sensing element. Its use in semiconductors is less common but explores its electronic properties.

When handling (1-Methyl-1H-indazol-6-YL)methanol, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up carefully using absorbent materials, and the area should be thoroughly rinsed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.