2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate

Basic Information

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CAS Number

108467-99-8

Molecular Formula

C13H20N2O2

Molecular Weight

236.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

250 °C

Refractive Index

n20/D 1.523(lit.)

SMILES

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CC(C)(C)OC(=O)NCC1=CC=CC(=C1)CN

InChI

InChI=1S/C13H20N2O2/c1-13(2,3)17-12(16)15-9-11-6-4-5-10(7-11)8-14/h4-7H,8-9,14H2,1-3H3,(H,15,16)

InChIKey

GQAUPTTUSSLXPS-UHFFFAOYSA-N

LogP

2.17

Topological Polar Surface Area

64.35 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

248

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

tert-Butyl {[3-(aminomethyl)phenyl]methyl}carbamate
3-(BOC-AMINOMETHYL)-BENZYLAMINE
CHEMBL4925342
108467-99-8
N-BOC-m-xylylenediamine
tert-ButylN-[3-(aminomethyl)benzyl]carbamate
tert-Butyl N-3-(AMINOmethyl)BENZYLCARBAMATE
3-(3-(aminomethyl)benzyl)-5-methyl-1,3-oxazinan-2-one
GQAUPTTUSSLXPS-UHFFFAOYSA-N
N-Boc-3-(aminomethyl)benzylamine
tert-butyl n-(3-(aminomethyl)benzyl)carbamate
(3-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
3-(tert-butyloxycarbonylaminomethyl)benzylamine
AS-38623
MFCD01317800
AC-6540
DTXSID40373205
1-(N-Boc-aminomethyl)-3-(aminomethyl)benzene
tert-butyl n-[3-(aminomethyl)benzyl] carbamate
FT-0642658
Tert-butyl N-[[3-(aminomethyl)phenyl]methyl]carbamate
tert-Butyl N-[3-(aminomethyl)benzyl]carbamate
tert-butyl 3-(amino methyl)benzylcarbamate
3-[N-(t-butyloxycarbonyl)aminomethyl]benzylamine
EN300-223022
3-(N-tert-butoxycarbonylaminomethyl)benzylamine
Tert-Butyl N-{[3-(Aminomethyl)Phenyl]Methyl}Carbamate
tert-butyl-n-(3-(aminomethyl) benzyl)carbamate
1-(N-Boc-aminomethyl)-3-(aminomethyl)benzene, 97%
1,1-dimethylethyl {[3-(aminomethyl)phenyl]methyl}carbamate
AKOS005256640

MDL Number

MFCD01317800

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate (CAS: 108467-99-8)?

2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate has a crystalline form and a molecular weight of approximately 298.4 g/mol. It is poorly soluble in water but soluble in organic solvents such as ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo hydrolysis under basic conditions.

How is 2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate (CAS: 108467-99-8) typically synthesized?

This compound can be synthesized through a multistep process involving the coupling of an amine with a carbamate precursor. Commonly used catalysts include bases like sodium hydride and solvents like dimethylformamide (DMF). The reaction typically proceeds with good selectivity and moderate to high yield.

What industries use 2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate (CAS: 108467-99-8)?

2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate is used in the pharmaceutical industry for intermediate synthesis and in the polymer industry for functionalization. It also has applications in sensor technology and semiconductor manufacturing as a functional group for modification.

What precautions should be taken when handling 2-Methyl-2-propanyl [3-(aminomethyl)benzyl]carbamate (CAS: 108467-99-8)?

When handling this compound, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a fume hood to avoid inhalation. In case of a spill, neutralize with appropriate acids or bases and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.