Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 | CAS No. 108437-87-2
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2
Basic Information
CAS Number
108437-87-2
Molecular Formula
C74H112N22O18S
Molecular Weight
1629.9 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 12-Phe-bombesin
- AKOS024456850
- (D-Phe12)-Bombesin
- [D-Phe12]-Bombesin
- PD079209
- PYR-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2
- Bombesin, 12-D-phenylalanine
- 108437-87-2
- Bombesin, phenylalanine(12)-
- Bombesin, phe(12)-
- Bombesin,12-D-phenylalanine-
- (D-Phe??)-Bombesin
- (D-PHE12)-BOMBESIN
- Bombesin,12-D-phenylalanine
- GLP-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-DPHE-LEU-MET-NH2
- M.W. 1629.90 C74H112N22O18S
- PGLU-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-D-PHE-LEU-MET-NH2
- PYR-QRLGNQWAVGFLM-NH2
- GLP-GLN-ARG-LEU-GLY-ASN-GLN-TRP-ALA-VAL-GLY-DPHE-LEU-MET-NH2: GLP-QRLGNQWAVG-DF-LM-NH2
- bombesin, Phe(12)-
FAQ
What are the physical and chemical properties of Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2)?
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 is a cyclic heptapeptide with a molecular weight of approximately 1145 Da. It has a crystalline form and is highly insoluble in water. This compound exhibits limited reactivity in aqueous solutions, with potential for condensation reactions under certain conditions. It is important to store it in a dry, cool place away from direct sunlight to preserve its integrity.
How is Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2) typically synthesized?
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly, this process involves sequential coupling of protected amino acids, followed by deprotection and cleavage from the solid support. The use of diisopropylcarbodiimide (DIC) as a coupling reagent and HOBt as a coupling enhancer is typical. The final product is purified via HPLC to ensure high purity.
What industries use Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2)?
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 is primarily used in the pharmaceutical industry for its potential as a peptide-based drug candidate. It is also of interest in the biotechnology sector for its use in protein engineering and in the development of peptide-based sensors and semiconductors. Its unique structure makes it a valuable compound for research in these fields.
What precautions should be taken when handling Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2)?
When handling Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2), it is essential to use personal protective equipment (PPE) such as gloves, lab coat, and safety glasses. This compound should be stored in a cool, dry place, away from direct sunlight and moisture. In case of a spill, it should be cleaned up carefully with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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