Compound Q&A
How is Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 (CAS: 108437-87-2) typically synthesized?
Answer
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2 is synthesized via solid-phase peptide synthesis (SPPS) using Fmoc chemistry. Commonly, this process involves sequential coupling of protected amino acids, followed by deprotection and cleavage from the solid support. The use of diisopropylcarbodiimide (DIC) as a coupling reagent and HOBt as a coupling enhancer is typical. The final product is purified via HPLC to ensure high purity.
About
CAS No
108437-87-2
English Name
Pyr-gln-arg-leu-gly-asn-gln-trp-ala-val-gly-D-phe-leu-met-NH2
Molecular Formula
C74H112N22O18S
Molecular Weight
1629.9 g/mol
SMILES
CC(C)CC(C(=O)NCC(=O)NC(CC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)N)NC(=O)C4CCC(=O)N4
InChIKey
NXZVGUQLNAVPLJ-VKXSZNMLSA-N
Last Updated: 2026-03-17 15:30
