Ambrisentan Impurity 2

Basic Information

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CAS Number

108-79-2

Molecular Formula

C6H8N2O

Molecular Weight

124.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

199.0 to 204.0 deg-C

Boiling Point

314.6℃ at 760 mmHg

Refractive Index

1.5378 (estimate)

SMILES

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CC1=CC(=NC(=O)N1)C

InChI

InChI=1S/C6H8N2O/c1-4-3-5(2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)

InChIKey

WHEQVHAIRSPYDK-UHFFFAOYSA-N

LogP

0.3867399999999999

Topological Polar Surface Area

45.75 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

203

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Q27279911
MFCD00006072
4,6-dimethyl-1,2-dihydropyrimidin-2-one
2-hydroxy-4 pound not6-dimethylpyrimidine
FT-0617261
AC-907/25014135
UNII-HG0CBN4V9F
AC7716
AKOS000117992
Z240985804
DS-11123
CS-W013526
4,6-Dimethyl-pyrimidin-2-ol
DTXSID5043762
108-79-2
4,6-Dimethyl-2-pyrimidinol
4,6-dimethyl-2(1H)-pyrimidinone
BP-10055
EINECS 203-617-5
2-Hydroxy-4,6-dimethyl pyrimidine
4,6-dimethyl-2(1h)-pyrimidone
A15497
4,6-dimethylpyrimidin-2(1H)-one
4,6-dimethyl-1H-pyrimidin-2-one
4,6-Dimethylpyrimidin-2-ol
CHEMBL3706457
BB 0243411
FT-0617262
4,6-Dimethyl-2-hydroxypyrimidine
AKOS000121150
2-PYRIMIDINOL, 4,6-DIMETHYL-

MDL Number

MFCD00006072

Customs Code

2933599090

FAQ

What regulatory guidelines apply to Ambrisentan Impurity 2 (CAS: 108-79-2)?

Ambrisentan Impurity 2 (CAS: 108-79-2) is subject to various regulatory guidelines such as GHS (Global Harmonized System of Classification and Labeling of Chemicals), REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in the European Union, and FDA/EPA (Food and Drug Administration/EPA) regulations in the United States. These guidelines cover safety data sheets, transport, and environmental protection requirements.

Are there alternatives to Ambrisentan Impurity 2 (CAS: 108-79-2) in synthesis?

In synthesis, alternatives to Ambrisentan Impurity 2 (CAS: 108-79-2) include the use of isomers or analogs such as Ambrisentan itself or related compounds. Additionally, substituting with common reagents like acetic anhydride or other amide-forming agents can be considered based on the specific synthesis conditions.

What is the market or research trend for Ambrisentan Impurity 2 (CAS: 108-79-2)?

The market for Ambrisentan Impurity 2 (CAS: 108-79-2) is closely associated with the broader market for Ambrisentan, a pulmonary arterial hypertension drug. Research trends focus on understanding its role in drug metabolism, its potential in drug development, and the impact of impurities on drug efficacy and safety. Market dynamics show a steady demand, with increasing emphasis on quality control and purity levels.

How should waste containing Ambrisentan Impurity 2 (CAS: 108-79-2) be handled?

Waste containing Ambrisentan Impurity 2 (CAS: 108-79-2) should be handled by collecting it in appropriate containers and disposing of it through professional waste disposal services. Incineration or chemical treatment may be necessary to ensure environmental safety. Follow local regulations for hazardous waste disposal to minimize environmental impact and comply with legal requirements.