What regulatory guidelines apply to Ambrisentan Impurity 2 (CAS: 108-79-2)?

Ambrisentan Impurity 2 (CAS: 108-79-2) is subject to various regulatory guidelines such as GHS (Global Harmonized System of Classification and Labeling of Chemicals), REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in the European Union, and FDA/EPA (Food and Drug Administration/EPA) regulations in the United States. These guidelines cover safety data sheets, transport, and environmental protection requirements.