(5,6-Dichloro-3-pyridinyl)boronic acid

Basic Information

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CAS Number

1072944-15-0

Molecular Formula

C5H4BCl2NO2

Molecular Weight

191.81 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

364.1℃ at 760 mmHg

SMILES

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B(C1=CC(=C(N=C1)Cl)Cl)(O)O

InChI

InChI=1S/C5H4BCl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2,10-11H

InChIKey

DRJYUOQTLCPXHE-UHFFFAOYSA-N

LogP

0.06819999999999982

Topological Polar Surface Area

53.35000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

138

Synonyms & References

English

AB44908
2,3-Dichloropyridine-5-boronicAcid
EN300-6772818
5,6-DICHLOROPYRIDINE-3-BORONIC ACID
SCHEMBL3340525
FT-0650027
AC-33488
SY108375
AMY7935
(5,6-DICHLOROPYRIDIN-3-YL)BORONIC ACID
AKOS006288393
2,3-DICHLOROPYRIDINE-5-BORONIC ACID
MFCD08277308
1072944-15-0
DRJYUOQTLCPXHE-UHFFFAOYSA-N
Boronic acid, B-(5,6-dichloro-3-pyridinyl)-
CS-0063135
5,6-dichloropyridin-3-ylboronic acid
DTXSID80671959
DS-11121
2,3-Dichloropyridine-5-boronic acid
(5,6-dichloropyridin-3-yl)boronic acid
5,6-Dichloropyridine-3-boronic acid
(5,6-dichloro-3-pyridyl)boronic acid
PubChem17070
5,6-Dichloropyridine-3-boronicacid
FCH859252
(5,6-dichloro-3-pyridinyl)boronic acid
OR361116
(5,6-dichloro-3-pyridinyl)boronic a

MDL Number

MFCD08277308

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0)?

(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) is a crystalline solid with a molecular weight of approximately 225.04 g/mol. This compound has a solubility of about 1.5 g/L in water and is moderately soluble in common organic solvents. It exhibits moderate reactivity, particularly in nucleophilic addition and substitution reactions. This boronic acid is known for its use in organic synthesis and catalysis.

How is (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) typically synthesized?

(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) is synthesized via a straightforward route involving the condensation of 3-chloropyridine with boronic acid in the presence of a suitable catalyst. Common methods include the use of palladium catalysts in the presence of triphenylphosphine and anhydrous conditions. The reaction typically yields a high degree of purity and selectivity, with excellent yields.

What industries use (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0)?

(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) finds applications in various industries. It is widely used in the pharmaceutical industry for the synthesis of biologically active compounds. In the polymer industry, it serves as a monomer for creating specialized materials. Additionally, this compound is utilized in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0)?

When handling (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. This compound should be stored in a cool, dry place, away from direct sunlight. In case of spills, use appropriate absorbent materials and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.