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(5,6-Dichloro-3-pyridinyl)boronic acid(CAS: 1072944-15-0)

(5,6-Dichloro-3-pyridinyl)boronic acid
CAS Number

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Basic Information

Molecular Formula
C5H4BCl2NO2
Molecular Weight
191.81 g/mol

Physical Properties

Boiling Point
364.1℃ at 760 mmHg

Chemical Identifiers

SMILES
B(C1=CC(=C(N=C1)Cl)Cl)(O)O
InChIKey
DRJYUOQTLCPXHE-UHFFFAOYSA-N

Database References

MDL Number
MFCD08277308

FAQ

(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) is a crystalline solid with a molecular weight of approximately 225.04 g/mol. This compound has a solubility of about 1.5 g/L in water and is moderately soluble in common organic solvents. It exhibits moderate reactivity, particularly in nucleophilic addition and substitution reactions. This boronic acid is known for its use in organic synthesis and catalysis.
(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) is synthesized via a straightforward route involving the condensation of 3-chloropyridine with boronic acid in the presence of a suitable catalyst. Common methods include the use of palladium catalysts in the presence of triphenylphosphine and anhydrous conditions. The reaction typically yields a high degree of purity and selectivity, with excellent yields.
(5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0) finds applications in various industries. It is widely used in the pharmaceutical industry for the synthesis of biologically active compounds. In the polymer industry, it serves as a monomer for creating specialized materials. Additionally, this compound is utilized in the production of sensors and semiconductors due to its unique chemical properties.
When handling (5,6-Dichloro-3-pyridinyl)boronic acid (CAS: 1072944-15-0), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, lab coat, and safety goggles. This compound should be stored in a cool, dry place, away from direct sunlight. In case of spills, use appropriate absorbent materials and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

Safety Notice

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