Aspartame Impurity 1 (Glycine Anhydride)

Basic Information

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CAS Number

106-57-0

Molecular Formula

C4H6N2O2

Molecular Weight

114.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

>300 °C

Boiling Point

213.59°C (rough estimate)

Water Solubility

Soluble in water (142mg/L).

Flash Point

301.9±28.3 °C

Solubility

142g/l

Refractive Index

1.4487 (estimate)

Vapor Pressure

0.0±1.6 mmHg at 25°C

SMILES

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C1C(=O)NCC(=O)N1

InChI

InChI=1S/C4H6N2O2/c7-3-1-5-4(8)2-6-3/h1-2H2,(H,5,8)(H,6,7)

InChIKey

BXRNXXXXHLBUKK-UHFFFAOYSA-N

LogP

-1.7675999999999992

Topological Polar Surface Area

58.2 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

116

Safety Information

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Hazard Statement

Synonyms & References

English

.alpha.,.gamma.-Diacipiperazine
SCHEMBL66638
CHEMBL125229
piperazine-2,5-quinone
NS00015771
2,5-Diazacyclohexane-1,4-dione
CS-0046695
F11382
240L69DTV7
alpha,gamma-Diacipiperazine
AKOS001056505
Glycine Anhydride(2,5-Piperazinedione)
EU-0051025
FT-0610501
BB 0266625
5-24-05-00294 (Beilstein Handbook Reference)
AC-907/30002028
Glycocoll Anhydride
2,5-Piperazinedione
Cyclic(glycylglycyl)
EINECS 203-411-5
Glycine, cyclic peptide
C02777
G-4600
NSC 26345
diglycolyldiamide
2,5-Dioxopiperazine
EN300-16993
UNII-240L69DTV7
NSC26345
Piperazine-2,5-dione (Glycine Anhydride)

MDL Number

MFCD00006009

Customs Code

2933599090

FAQ

What is Aspartame Impurity 1 (CAS: 106-57-0)?

Aspartame Impurity 1, also known as Glycine Anhydride, is a chemical compound with the CAS number 106-57-0. It is an anhydride derivative of glycine and is commonly found as a byproduct during the synthesis of aspartame, an artificial sweetener. This compound is a white crystalline solid with a molecular formula of C2H3NO2 and is used primarily in analytical testing to identify and quantify impurities in aspartame products.

What are the main uses of Aspartame Impurity 1 (CAS: 106-57-0)?

Aspartame Impurity 1 (CAS: 106-57-0) is mainly used in the pharmaceutical and food industries for quality control and purity testing of aspartame. It serves as a reference standard in analytical chemistry to detect and measure impurities, ensuring the safety and consistency of the final product. Additionally, it is used in research to study the degradation pathways and stability of aspartame under various conditions.

Is Aspartame Impurity 1 (CAS: 106-57-0) safe?

Aspartame Impurity 1 (CAS: 106-57-0) is generally considered safe when used in controlled laboratory settings. However, as with any chemical, it should be handled with appropriate precautions, such as wearing protective gloves and goggles. While it is not classified as toxic in typical exposure scenarios, safety standards recommend avoiding prolonged contact with skin or inhalation of its dust. It is important to follow standard safety protocols for chemical handling.

How should Aspartame Impurity 1 (CAS: 106-57-0) be stored?

Aspartame Impurity 1 (CAS: 106-57-0) should be stored in a cool, dry, and well-ventilated place, away from moisture and direct light. It is best kept in a sealed container at a temperature below 25°C to maintain stability. Proper storage conditions are essential to prevent decomposition and ensure the compound remains suitable for analytical purposes.