5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one | CAS No. 1058653-74-9
5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Basic Information
CAS Number
1058653-74-9
Molecular Formula
C19H21ClN4O3
Molecular Weight
388.86 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
193 ºC (benzene )
Synonyms & References
English
- 5-(5-(2-Chloroacetyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
- Chlorodenafil
- 5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one
- 5-[5-(2-chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
- Sildenafil Impurity 5
- 5-(5-(2-chloroacetyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
MDL Number
MFCD21363818
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS: 1058653-74-9)?
The compound has a crystalline form with a molecular weight of approximately 451.26 g/mol. It is slightly soluble in water and more soluble in organic solvents such as methanol and acetonitrile. The compound is moderately reactive, particularly towards hydrolysis and nucleophilic substitution reactions.
How is 5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS: 1058653-74-9) typically synthesized?
The compound is synthesized through a multi-step process involving the reaction of 2-ethoxyphenyl chloroacetate with 1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7-one. The synthesis involves the use of a base such as sodium hydride and proceeds with moderate yield (around 70-75%).
What industries use 5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS: 1058653-74-9)?
The compound is used in the pharmaceutical industry for its potential therapeutic applications. It may also have applications in the polymer industry for its possible use as a cross-linking agent or in the development of smart materials.
What precautions should be taken when handling 5-[5-(Chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (CAS: 1058653-74-9)?
When handling the compound, appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood. In case of spill, it should be carefully cleaned up using appropriate absorbent materials and disposed of according to local regulations. An SDS (Safety Data Sheet) should be consulted for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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