2-chloro-9H-carbazole

Basic Information

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CAS Number

10537-08-3

Molecular Formula

C12H8ClN

Molecular Weight

201.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

243.0 to 247.0 deg-C

Boiling Point

388.7°C at 760 mmHg

Solubility

Insuluble (1.7E-3 g/L) (25 ºC),

SMILES

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C1=CC=C2C(=C1)C3=C(N2)C=C(C=C3)Cl

InChI

InChI=1S/C12H8ClN/c13-8-5-6-10-9-3-1-2-4-11(9)14-12(10)7-8/h1-7,14H

InChIKey

LOQQFCPPDBFFSO-UHFFFAOYSA-N

LogP

3.9745000000000017

Topological Polar Surface Area

15.79 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

218

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-chloro-9H-Carbazole
2-Chlorocarbazole
2-Chlor-carbazol
3-chlorocarbazole
9H-Carbazole,2-chloro
2-chloroarbazole
9H-Carbazole, 2-chloro-
AK316321
2-chlorcarbazol
LOQQFCPPDBFFSO-UHFFFAOYSA-N
FCH1332684
OR340088
DB-104514
AMY8697
10537-08-3
C12H8ClN
CHEMBL5076887
InChI=1/C12H8ClN/c13-8-5-6-10-9-3-1-2-4-11(9)14-12(10)7-8/h1-7,14
C3362
DTXSID40372894
CS3413
2-chloro-9H-carbazole
AKOS004902077
GS-0700
SCHEMBL4670015
CS-0042719
MFCD01444890
EN300-226396

MDL Number

MFCD01444890

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-chloro-9H-carbazole (CAS: 10537-08-3)?

2-Chloro-9H-carbazole (CAS: 10537-08-3) is a solid with a crystalline form. Its molecular weight is approximately 172.56 g/mol. It has limited water solubility but is more soluble in polar solvents like dimethylformamide and dimethylsulfoxide. This compound exhibits high thermal stability and moderate reactivity, particularly towards nucleophilic substitution reactions.

How is 2-chloro-9H-carbazole (CAS: 10537-08-3) typically synthesized?

2-Chloro-9H-carbazole (CAS: 10537-08-3) is commonly synthesized via a multistep process involving the condensation of 3-chloro-1,2-dihydronaphthalene with aniline, followed by amination and chlorination reactions. This process uses catalysts like palladium(II) acetate to improve selectivity and yield.

What industries use 2-chloro-9H-carbazole (CAS: 10537-08-3)?

2-Chloro-9H-carbazole (CAS: 10537-08-3) is widely used in the pharmaceutical industry for the synthesis of drugs. It also finds applications in the polymer industry for the production of specialized polymers. Additionally, it is used in the development of sensors and semiconductors, particularly in organic electronic devices.

What precautions should be taken when handling 2-chloro-9H-carbazole (CAS: 10537-08-3)?

When handling 2-chloro-9H-carbazole (CAS: 10537-08-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate cleaning agents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for specific guidelines.