6-Amino-N-methyl-2-naphthalenesulfonamide

Basic Information

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CAS Number

104295-55-8

Molecular Formula

C11H12N2O2S

Molecular Weight

236.3 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

157-163 ºC

SMILES

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CNS(=O)(=O)C1=CC2=C(C=C1)C=C(C=C2)N

InChI

InChI=1S/C11H12N2O2S/c1-13-16(14,15)11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7,13H,12H2,1H3

InChIKey

RBQODZRXIYFUJS-UHFFFAOYSA-N

LogP

1.3301

Topological Polar Surface Area

72.19 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

336

Synonyms & References

English

6-amino-N-methylnaphthalene-2-sulfonamide
2-Naphthylamine-6-sulfonylmethylamine
A800950
2-Naphthalene Sulfonamide-6-Amino-N-Methyl
DTXSID70888817
2-Naphthalenesulfonamide, 6-amino-N-methyl-
CS-0440160
EC 412-120-4
2-Naphthylamine-6-sulfomethylamide
2-Naphthylamine-6-sulfonmethylamide
6-Methylaminosulfonyl-2-naphthylamine
2-Naphthylamine-6-sulfonylmethylamide
FT-0656445
NS00001088
AKOS015897370
SCHEMBL9404993
104295-55-8
6-Amino-N-methylnaphthalene-2-sulfonamide
2-naphthylamine-6-sulfon-methylamide
6-amino-N-methyl-2-Naphthalenesulfonamide

MDL Number

MFCD02684427

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 6-Amino-N-methyl-2-naphthalenesulfonamide (CAS: 104295-55-8)?

6-Amino-N-methyl-2-naphthalenesulfonamide is a crystalline solid with a molecular weight of approximately 262.23 g/mol. It has a solubility of about 7.5 mg/mL in water. The compound is moderately reactive, particularly under basic conditions. It is insoluble in common organic solvents such as dichloromethane and ethanol.

How is 6-Amino-N-methyl-2-naphthalenesulfonamide (CAS: 104295-55-8) typically synthesized?

6-Amino-N-methyl-2-naphthalenesulfonamide can be synthesized via the sulfonation of 2-naphthol followed by amide coupling. The sulfonation step is catalyzed by concentrated sulfuric acid, and the coupling reaction involves the use of a suitable amine, often in the presence of a base like sodium hydroxide. The overall yield is generally around 75%.

What industries use 6-Amino-N-methyl-2-naphthalenesulfonamide (CAS: 104295-55-8)?

6-Amino-N-methyl-2-naphthalenesulfonamide is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It also finds applications in the polymer industry as a dye precursor, and in the sensor and semiconductor industries due to its electronic properties.

What precautions should be taken when handling 6-Amino-N-methyl-2-naphthalenesulfonamide (CAS: 104295-55-8)?

When handling 6-Amino-N-methyl-2-naphthalenesulfonamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with water and proper waste handling procedures should be followed. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.