5-Bromo-8-methoxy-2-methylquinoline

Basic Information

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CAS Number

103862-55-1

Molecular Formula

C11H10BrNO

Molecular Weight

252.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

114 ºC

Boiling Point

341 ºC

Flash Point

160 ºC

SMILES

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CC1=NC2=C(C=CC(=C2C=C1)Br)OC

InChI

InChI=1S/C11H10BrNO/c1-7-3-4-8-9(12)5-6-10(14-2)11(8)13-7/h3-6H,1-2H3

InChIKey

MCBRCJBMVOOJFX-UHFFFAOYSA-N

LogP

3.314320000000002

Topological Polar Surface Area

22.12 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

200

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Bromo-8-methoxy-2-methylquinoline
5-BROMO-8-METHYLQUINOLINE
5-BROMO-8-METHOXY-2-METHYL-QUINOLINE
MCBRCJBMVOOJFX-UHFFFAOYSA-N
BBL020679
2-Methyl-5-bromo-8-methoxyquinoline
STK893369
RL00187
FCH1328493
ST2406149
AX8212458
AB0059400
Z6695
H8129
F20610
MFCD04966993
AMY10960
J-517147
CS-0152760
SB71730
5-bromo-8-methoxy-2-methylquinoline
103862-55-1
AKOS001476131
AC-23706
ZB0071
DS-2366
SCHEMBL681786
DB-059063
DTXSID20405811
A26259
5-bromo-8-methoxy-2-methyl-quinoline

MDL Number

MFCD04966993

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1)?

5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1) is a crystalline solid with a molecular weight of approximately 265.04 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards nucleophiles and electrophiles, and can undergo substitution reactions under mild conditions.

How is 5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1) typically synthesized?

5-Bromo-8-methoxy-2-methylquinoline is typically synthesized through a multistep process involving alkylation of 8-hydroxy-2-methylquinoline followed by bromination. The synthesis often uses bromine in pyridine as a brominating agent, and the reaction is carried out under nitrogen to avoid oxidation. The overall yield is moderate, around 60-70%, with good selectivity towards the brominated product.

What industries use 5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1)?

5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1) finds applications in the pharmaceutical industry for the synthesis of certain bioactive compounds. It is also used in the preparation of sensors and semiconductors due to its electronic properties. Additionally, it is relevant in the polymer industry for the development of novel functional materials.

What precautions should be taken when handling 5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1)?

When handling 5-Bromo-8-methoxy-2-methylquinoline (CAS: 103862-55-1), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or within a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the area should be washed down. Always refer to the Safety Data Sheet (SDS) for specific handling and emergency procedures.