(1R)-1-Indanamine

Basic Information

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CAS Number

10277-74-4

Molecular Formula

C9H11N

Molecular Weight

133.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

15 °C

Boiling Point

96-97 °C/8 mmHg

Water Solubility

Soluble in methanol. Not miscible or difficult to mix in water.

Refractive Index

n20/D 1.562(lit.)

Specific Rotation

-20 º (c=1.5, MeOH)

SMILES

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C1CC2=CC=CC=C2C1N

InChI

InChI=1S/C9H11N/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9H,5-6,10H2/t9-/m1/s1

InChIKey

XJEVHMGJSYVQBQ-SECBINFHSA-N

LogP

1.6326

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

122

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Sensitiveness

Air Sensitive

Synonyms & References

English

(R)-(-)-1-Aminoindane, 97%
(R)-1-Aminoindane, 90per cent ee
(R)-(-)-aminoindane
(R)-(-)-INDANAMINE
Q27280240
AKOS006240503
10277-74-4
1-(r)-aminoindan
(1R)-1-Indanamine
(R)(-)-1-aminoindane
AM62791
AC-6132
(1r)-1-aminoindane
(r)-1-amino-indane
(1R)-2,3-Dihydro-1H-inden-1-ylamine
(R)-2,3-dihydro-1H-inden-1-amine
(R)-1-Aminoindane
R-AI
I17RC77CJ2
((1R)-2,3-Dihydro-1H-inden-1-yl)amine
(R)-INDAN-1-YLAMINE
UNII-I17RC77CJ2
(R)-1-Aminoindan
(1R)-2,3-dihydro-1H-inden-1-amine
1-Aminoindan, (-)-
DTXSID70370045
CHEMBL4573666
SCHEMBL42279
(R)-(-)-1-amino indan
1-AMINOINDANE, (R)-
(R)-1-Indanamine

MDL Number

MFCD00216669

Customs Code

2921499090

FAQ

What are the physical and chemical properties of (1R)-1-Indanamine (CAS: 10277-74-4)?

(1R)-1-Indanamine is a colorless crystalline solid with a molecular weight of approximately 138.21 g/mol. It has a melting point of 88-90°C and a solubility of 1.3 g/100 mL in water. It is less reactive compared to other amines but can undergo electrophilic aromatic substitution reactions. Its stability in air and light is good.

How is (1R)-1-Indanamine (CAS: 10277-74-4) typically synthesized?

(1R)-1-Indanamine is typically synthesized via the reduction of 1-indanone with sodium borohydride. The reaction is conducted in tetrahydrofuran (THF) solvent at room temperature. The yield is around 70-75%, and the enantiomeric purity can be improved using chiral chromatographic techniques.

What industries use (1R)-1-Indanamine (CAS: 10277-74-4)?

(1R)-1-1-Indanamine is primarily used in the pharmaceutical industry for the synthesis of certain drug compounds. It is also utilized in the polymer industry as a monomer for the production of specialty polymers. Additionally, it has applications in the sensor and semiconductor industries due to its unique chemical properties.

What precautions should be taken when handling (1R)-1-Indanamine (CAS: 10277-74-4)?

When handling (1R)-1-Indanamine, appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles should be worn. The compound should be handled in a well-ventilated area or in a fume hood. In case of a spill, it should be immediately cleaned up with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.