(1R)-1-Indanamine(CAS: 10277-74-4)

(1R)-1-Indanamine is a colorless crystalline solid with a molecular weight of approximately 138.21 g/mol. It has a melting point of 88-90°C and a solubility of 1.3 g/100 mL in water. It is less reactive compared to other amines but can undergo electrophilic aromatic substitution reactions. Its stability in air and light is good.

(1R)-1-Indanamine is typically synthesized via the reduction of 1-indanone with sodium borohydride. The reaction is conducted in tetrahydrofuran (THF) solvent at room temperature. The yield is around 70-75%, and the enantiomeric purity can be improved using chiral chromatographic techniques.

(1R)-1-1-Indanamine is primarily used in the pharmaceutical industry for the synthesis of certain drug compounds. It is also utilized in the polymer industry as a monomer for the production of specialty polymers. Additionally, it has applications in the sensor and semiconductor industries due to its unique chemical properties.

When handling (1R)-1-Indanamine, appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles should be worn. The compound should be handled in a well-ventilated area or in a fume hood. In case of a spill, it should be immediately cleaned up with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.