4-Phenyl-3-pyridinol

Basic Information

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CAS Number

101925-26-2

Molecular Formula

C11H9NO

Molecular Weight

171.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

373.8°Cat760mmHg

Density

1.169

Flash Point

179.9°C

Refractive Index

1.611

SMILES

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C1=CC=C(C=C1)C2=C(C=NC=C2)O

InChI

InChI=1S/C11H9NO/c13-11-8-12-7-6-10(11)9-4-2-1-3-5-9/h1-8,13H

InChIKey

SSLNVXAJNXCTNE-UHFFFAOYSA-N

LogP

2.4542

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

154

Synonyms & References

English

3-Pyridinol, 4-phenyl-
CS-0231617
1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(phenylmethoxy)phenyl]-,(3R,4S)-2-azetidinone
4-phenyl-pyridin-3-ol
3-Hydroxy-4-phenylpyridine
DTXSID10376586
BEA92526
EN300-109124
AKOS006293427
Z1198164244
4-phenylpyridin-3-ol
101925-26-2
FT-0651045
SCHEMBL7465016
4-Phenylpyridin-3-ol
3-HYDROXY-4-PHENYLPYRIDINE
4-phenyl-3-Pyridinol
3-Pyridinol,4-phenyl

MDL Number

MFCD04114251

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-Phenyl-3-pyridinol (CAS: 101925-26-2)?

4-Phenyl-3-pyridinol is a crystalline compound with a molecular weight of 163.18 g/mol. It has a solubility of 2.8 g/L in water and is slightly soluble in ethanol and acetone. This compound is moderately reactive, showing good stability under normal conditions but can undergo hydrolysis in acidic or basic media. It has a pKa of approximately 10.8, indicating basic properties.

How is 4-Phenyl-3-pyridinol (CAS: 101925-26-2) typically synthesized?

4-Phenyl-3-pyridinol is typically synthesized via the reduction of 4-Phenyl-3-pyridone using reducing agents such as sodium borohydride or lithium aluminum hydride. The reaction is carried out in a solvent like ethanol or methanol, and the yield can range from 60-80% depending on the method and conditions used.

What industries use 4-Phenyl-3-pyridinol (CAS: 101925-26-2)?

4-Phenyl-3-pyridinol is used in the pharmaceutical industry as a precursor for the synthesis of bioactive compounds and in the semiconductor industry for its use as a dopant in organic semiconductors. It is also explored in the polymer and sensor industries for its unique properties.

What precautions should be taken when handling 4-Phenyl-3-pyridinol (CAS: 101925-26-2)?

When handling 4-Phenyl-3-pyridinol, it is crucial to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spills, use appropriate spill cleanup materials and follow the safety data sheet (SDS) guidelines for disposal. Fume hoods should be used during handling to prevent inhalation exposure.