4-Phenyl-3-pyridinol(CAS: 101925-26-2)

4-Phenyl-3-pyridinol is a crystalline compound with a molecular weight of 163.18 g/mol. It has a solubility of 2.8 g/L in water and is slightly soluble in ethanol and acetone. This compound is moderately reactive, showing good stability under normal conditions but can undergo hydrolysis in acidic or basic media. It has a pKa of approximately 10.8, indicating basic properties.

4-Phenyl-3-pyridinol is typically synthesized via the reduction of 4-Phenyl-3-pyridone using reducing agents such as sodium borohydride or lithium aluminum hydride. The reaction is carried out in a solvent like ethanol or methanol, and the yield can range from 60-80% depending on the method and conditions used.

4-Phenyl-3-pyridinol is used in the pharmaceutical industry as a precursor for the synthesis of bioactive compounds and in the semiconductor industry for its use as a dopant in organic semiconductors. It is also explored in the polymer and sensor industries for its unique properties.

When handling 4-Phenyl-3-pyridinol, it is crucial to use proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spills, use appropriate spill cleanup materials and follow the safety data sheet (SDS) guidelines for disposal. Fume hoods should be used during handling to prevent inhalation exposure.