3,4-Pyridinediol

Basic Information

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CAS Number

10182-48-6

Molecular Formula

C5H5NO2

Molecular Weight

111.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

270.5ºC at 760mmHg

Density

1.379g/cm3

Flash Point

117.4ºC

Refractive Index

1.593

SMILES

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C1=CNC=C(C1=O)O

InChI

InChI=1S/C5H5NO2/c7-4-1-2-6-3-5(4)8/h1-3,8H,(H,6,7)

InChIKey

ZCUUVWCJGRQCMZ-UHFFFAOYSA-N

LogP

0.08049999999999996

Topological Polar Surface Area

53.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

169

Synonyms & References

English

3,3-dihydroxypyridine
AKOS006350882
NS00074032
3,4-Dihydroxypyridine
MFCD01691806
SB52682
Q27891533
AS-56719
CS-0155544
3,4-Pyridinediol
3-Hydroxy-4H-pyrid-4-one
DTXSID50274234
CHEBI:28630
3-Hydroxypyridin-4(1H)-one
C02932
BRN 0110211
3-Hydroxy-4-pyridone
SCHEMBL141070
3-Hydroxy-4(1H)-pyridinone
10182-48-6
FT-0650310
C03927
3,4-Dihydroxypyridin
CHEBI:29053
4(1H)-Pyridinone, 3-hydroxy-
A800461
AM85417
AKOS005264864
UW0C50CU4H
1121-23-9
Q-101867

MDL Number

MFCD01691806

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3,4-Pyridinediol (CAS: 10182-48-6)?

3,4-Pyridinediol (CAS: 10182-48-6) is a white crystalline solid with a molecular weight of approximately 122.12 g/mol. It is slightly soluble in water and has good solubility in polar organic solvents. Chemically, it is highly reactive due to the presence of hydroxyl groups, which can participate in various chemical reactions such as esterification, etherification, and condensation reactions.

How is 3,4-Pyridinediol (CAS: 10182-48-6) typically synthesized?

3,4-Pyridinediol can be synthesized via the condensation of pyridine and paraformaldehyde in the presence of a catalyst like sulfuric acid. The reaction selectively forms 3,4-pyridinedione, which can then be reduced to 3,4-pyridinediol using hydrogenation or other reduction methods. The overall yield is around 70-80%, with high selectivity towards the desired product.

What industries use 3,4-Pyridinediol (CAS: 10182-48-6)?

3,4-Pyridinediol (CAS: 10182-48-6) is widely used in the pharmaceutical industry for the synthesis of various drugs, including analgesics and antipyretics. It is also utilized in the production of polymers, particularly in the preparation of polyurethane prepolymers. Additionally, it has applications in sensor technology, where it serves as a functional material due to its reactivity with certain metal ions.

What precautions should be taken when handling 3,4-Pyridinediol (CAS: 10182-48-6)?

When handling 3,4-Pyridinediol (CAS: 10182-48-6), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and spill response procedures.