3,4-Pyridinediol(CAS: 10182-48-6)

3,4-Pyridinediol (CAS: 10182-48-6) is a white crystalline solid with a molecular weight of approximately 122.12 g/mol. It is slightly soluble in water and has good solubility in polar organic solvents. Chemically, it is highly reactive due to the presence of hydroxyl groups, which can participate in various chemical reactions such as esterification, etherification, and condensation reactions.

3,4-Pyridinediol can be synthesized via the condensation of pyridine and paraformaldehyde in the presence of a catalyst like sulfuric acid. The reaction selectively forms 3,4-pyridinedione, which can then be reduced to 3,4-pyridinediol using hydrogenation or other reduction methods. The overall yield is around 70-80%, with high selectivity towards the desired product.

3,4-Pyridinediol (CAS: 10182-48-6) is widely used in the pharmaceutical industry for the synthesis of various drugs, including analgesics and antipyretics. It is also utilized in the production of polymers, particularly in the preparation of polyurethane prepolymers. Additionally, it has applications in sensor technology, where it serves as a functional material due to its reactivity with certain metal ions.

When handling 3,4-Pyridinediol (CAS: 10182-48-6), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to vapors. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and spill response procedures.