2,5-Difluoro-4-iodopyridine

Basic Information

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CAS Number

1017793-20-2

Molecular Formula

C5H2F2IN

Molecular Weight

240.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

209.7℃ at 760 mmHg

SMILES

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c1c(c(cnc1F)F)I

InChI

InChI=1S/C5H2F2IN/c6-3-2-9-5(7)1-4(3)8/h1-2H

InChIKey

OBVRKNZQNKGNTQ-UHFFFAOYSA-N

LogP

1.9644

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

101

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2,5-Difluoro-4-iodopyridine
Pyridine,2,5-difluoro-4-iodo
QC-225
Pyridine, 2,5-difluoro-4-iodo-
2,5-difluoro-4-iodo-pyridine
PubChem22303
Difluoro-4-iodopyridine
BYS118
Pyridine,2,5-difluoro-4-iodo-
OBVRKNZQNKGNTQ-UHFFFAOYSA-N
BCP14926
STL556244
BBL102442
FCH1401566
PC53341
SY030496
AX8213074
AB0060793
Z6412
2,5-difluoro-4-iodopyridine

MDL Number

MFCD11040606

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,5-Difluoro-4-iodopyridine (CAS: 1017793-20-2)?

2,5-Difluoro-4-iodopyridine is a crystalline solid with a molecular weight of approximately 265.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. The compound is known for its reactivity, particularly in nucleophilic substitution reactions. It is stable under normal conditions but can react with strong nucleophiles.

How is 2,5-Difluoro-4-iodopyridine (CAS: 1017793-20-2) typically synthesized?

2,5-Difluoro-4-iodopyridine is typically synthesized via the reaction of 2,5-difluoropyridine with iodine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. This method provides a good balance between reactivity and safety.

What industries use 2,5-Difluoro-4-iodopyridine (CAS: 1017793-20-2)?

2,5-Difluoro-4-iodopyridine is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the polymer industry for the development of special polymers with unique properties. It also finds applications in the sensor and semiconductor industries due to its reactive nature and stable electronic structure.

What precautions should be taken when handling 2,5-Difluoro-4-iodopyridine (CAS: 1017793-20-2)?

Proper personal protective equipment (PPE) is essential when handling 2,5-Difluoro-4-iodopyridine, including gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.