5-Methoxy-2-pyridinamine

Basic Information

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CAS Number

10167-97-2

Molecular Formula

C6H8N2O

Molecular Weight

124.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

38°C

Boiling Point

130°C/10mmHg

Flash Point

106℃

SMILES

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COC1=CN=C(C=C1)N

InChI

InChI=1S/C6H8N2O/c1-9-5-2-3-6(7)8-4-5/h2-4H,1H3,(H2,7,8)

InChIKey

XJKJHILCYUUVSJ-UHFFFAOYSA-N

LogP

0.6723999999999999

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

87.1

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

W-204421
2-PYRIDINAMINE, 5-METHOXY-
2-Amino-5-methoxy-pyridine
DTXSID50462174
AKOS000222350
5-methoxy-2-aminopyridine
SY005382
SCHEMBL22074010
10167-97-2
A16281
PB14487
2-amino-5-methoxy pyridine
AC-5955
SCHEMBL333949
5-METHOXY-2-PYRIDINAMINE
5-methoxypyridin-2-amine
PS-5045
MFCD07374873
BCP21282
EN300-149707
AM807040
XJKJHILCYUUVSJ-UHFFFAOYSA-N
2-AMINO-5-METHOXYPYRIDINE
CS-D1544
J-400240
5-methoxypyridin-2-ylamine
FT-0650421
5-Methoxy-pyridin-2-ylamine
2-Amino-5-methoxypyridine
5-METHOXYPYRIDIN-2-AMINE
5-Methoxy-Pyridin-2-Ylamine

MDL Number

MFCD07374873

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Methoxy-2-pyridinamine (CAS: 10167-97-2)?

5-Methoxy-2-pyridinamine is a solid with a crystalline form. Its molecular weight is approximately 141.15 g/mol. It has limited water solubility, being slightly soluble in water. Chemically, it is mildly basic and can react with acidic compounds. It is stable under normal conditions but may degrade under acidic or basic conditions.

How is 5-Methoxy-2-pyridinamine (CAS: 10167-97-2) typically synthesized?

5-Methoxy-2-pyridinamine can be synthesized by the reaction of 2-pyridinemethanamine with methanol in the presence of an acid catalyst. The process involves nucleophilic substitution, leading to the formation of the methoxy group. The yield is typically around 85%, and the reaction is selective and efficient.

What industries use 5-Methoxy-2-pyridinamine (CAS: 10167-97-2)?

5-Methoxy-2-pyridinamine is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of sensors and as an intermediate in the synthesis of other pyridine derivatives for various applications, including polymers and semiconductors.

What precautions should be taken when handling 5-Methoxy-2-pyridinamine (CAS: 10167-97-2)?

Handling 5-Methoxy-2-pyridinamine requires the use of personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a closed, cool, and dry place. Spills should be contained and treated according to the Material Safety Data Sheet (MSDS). It is important to work in a well-ventilated area or a fume hood to minimize exposure to this compound.